Is it good to have a stiff aorta with aging? Causes and consequences

GL Pierce, TA Coutinho, LE DuBose… - Physiology, 2022 - journals.physiology.org
Aortic stiffness increases with advancing age, more than doubling during the human life
span, and is a robust predictor of cardiovascular disease (CVD) clinical events independent …

[HTML][HTML] Sympathetic neural modulation of arterial stiffness in humans

M Nardone, JS Floras, PJ Millar - American Journal of …, 2020 - journals.physiology.org
Elevated large-artery stiffness is recognized as an independent predictor of cardiovascular
and all-cause mortality. The mechanisms responsible for such stiffening are incompletely …

COVID‐19 is getting on our nerves: sympathetic neural activity and haemodynamics in young adults recovering from SARS‐CoV‐2

NL Stute, JL Stickford, VM Province… - The Journal of …, 2021 - Wiley Online Library
Key points The impact of SARS‐CoV‐2 infection on autonomic and cardiovascular function
in otherwise healthy individuals is unknown. For the first time it is shown that young adults …

Influence of sex and age on muscle sympathetic nerve activity of healthy normotensive adults

DA Keir, MB Badrov, G Tomlinson, CF Notarius… - …, 2020 - Am Heart Assoc
As with blood pressure, age-related changes in muscle sympathetic nerve activity (MSNA)
may differ nonlinearly between sexes. Data acquired from 398 male (age: 39±17; range: 18 …

Antiaging effects of aerobic exercise on systemic arteries

H Tanaka - Hypertension, 2019 - Am Heart Assoc
238 Hypertension August 2019 postmenopausal women20 to levels seen in age-matched
endurance-trained adults (Figure 2, red arrow). The ability of regular aerobic exercise to …

The sympathetic nervous system in heart failure revisited

F Triposkiadis, A Briasoulis, T Kitai, D Magouliotis… - Heart Failure …, 2024 - Springer
Several attempts have been made, by the scientific community, to develop a unifying
hypothesis that explains the clinical syndrome of heart failure (HF). The currently widely …

Age-and sex-related differences in sympathetic vascular transduction and neurohemodynamic balance in humans

AW D'Souza, SL Hissen, K Manabe… - American Journal …, 2023 - journals.physiology.org
Bursts of muscle sympathetic nerve activity (MSNA) and the ensuing vasoconstriction are
pivotal determinants of beat-by-beat blood pressure regulation. Although age and sex …

Clinical applications measuring arterial stiffness: an expert consensus for the application of cardio-ankle vascular index

MJ Budoff, B Alpert, JA Chirinos… - American journal of …, 2022 - academic.oup.com
BACKGROUND The purpose of this document is to provide clinicians with guidance, using
expert consensus, to help summarize evidence and offer practical recommendations …

[HTML][HTML] Hypertensive heart failure

F Triposkiadis, P Sarafidis, A Briasoulis… - Journal of Clinical …, 2023 - mdpi.com
Despite overwhelming epidemiological evidence, the contribution of hypertension (HTN) to
heart failure (HF) development has been undermined in current clinical practice. This is …

[HTML][HTML] Targeting autonomic nervous system as a biomarker of well-ageing in the prevention of stroke

JC Barthelemy, V Pichot, D Hupin, M Berger… - Frontiers in aging …, 2022 - frontiersin.org
Stroke prediction is a key health issue for preventive medicine. Atrial fibrillation (AF)
detection is well established and the importance of obstructive sleep apneas (OSA) has …