Summary c-MYC controls global gene expression and regulates cell proliferation, cell
differentiation, cell cycle, metabolism and apoptosis. According to some estimates, MYC is …

The MYC gene which consists of 3 paralogs, C-MYC, N-MYC and L-MYC, is one of the most
frequently deregulated driver genes in human cancer. Because of its high prevalence of …

Although the MYC oncogene has been implicated in cancer, a systematic assessment of
alterations of MYC, related transcription factors, and co-regulatory proteins, forming the …

In mammalian cells, the MYC oncoprotein binds to thousands of promoters,,,. During
mitogenic stimulation of primary lymphocytes, MYC promotes an increase in the expression …

Enhanced and deregulated expression of N-MYC, a member of the MYC family of
transcription factors, drives the development of multiple tumors, including tumors of the …

The c-myc gene was discovered as the cellular homolog of the retroviral v-myc oncogene 20
years ago (23, 25, 167). The c-myc proto-oncogene was subsequently found to be activated …

Cold‐induced expression of the Arabidopsis COR (cold‐regulated) genes is mediated by a
DNA regulatory element termed the CRT (C‐repeat)/DRE (dehydration‐responsive …

The Period2 gene plays a key role in controlling circadian rhythm in mice. We report here
that mice deficient in the mPer2 gene are cancer prone. After γ radiation, these mice show a …

The role of the myc gene family in the biology of normal and cancer cells has been
intensively studied since the early 1980s. myc genes, responding to diverse external and …

▪ Abstract The Myc/Max/Mad network comprises a group of transcription factors whose
distinct interactions result in gene-specific transcriptional activation or repression. A great …