Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
AA Elfiky - Life sciences, 2020 - Elsevier
Aims A new human coronavirus (HCoV), which has been designated SARS-CoV-2, began
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
AA Elfiky - Life sciences, 2020 - Elsevier
Aims A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan,
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective
AA Elfiky - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
New treatment against SARS-CoV-2 now is a must. Nowadays, the world encounters a huge
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
Structure-based drug design of RdRp inhibitors against SARS-CoV-2
K Shehzadi, A Saba, M Yu, J Liang - Topics in Current Chemistry, 2023 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
[HTML][HTML] In silico studies reveal potential antiviral activity of phytochemicals from medicinal plants for the treatment of COVID-19 infection
M Pandit, N Latha - 2020 - europepmc.org
The spread of COVID-19 across continents has led to a global health emergency. COVID-19
disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has …
disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has …
[HTML][HTML] Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach
Abstract The coronavirus disease 2019 (COVID-19), which emerged in December 2019,
continues to be a serious health concern worldwide. There is an urgent need to develop …
continues to be a serious health concern worldwide. There is an urgent need to develop …
[HTML][HTML] In silico molecular docking analysis for repurposing approved antiviral drugs against SARS-CoV-2 main protease
Developing a safe and effective antiviral treatment takes a decade, however, when it comes
to the coronavirus disease (COVID-19), time is a sensitive matter to slow the spread of the …
to the coronavirus disease (COVID-19), time is a sensitive matter to slow the spread of the …
[PDF][PDF] Anti-HIV and Anti-HCV drugs are the putative inhibitors of RNA-dependent-RNA polymerase activity of NSP12 of the SARS CoV-2 (COVID-19)
Corona virus is the emerging infectious viral agent that had to threaten the world with its
epidemic since 2003 with SARS and 2013 with MERS virus. This virus again stuck the whole …
epidemic since 2003 with SARS and 2013 with MERS virus. This virus again stuck the whole …
Molecular dynamics simulation revealed binding of nucleotide inhibitors to ZIKV polymerase over 444 nanoseconds
AA Elfiky, WM Elshemey - Journal of Medical Virology, 2018 - Wiley Online Library
In the year 2015, new Zika virus (ZIKV) broke out in Brazil and spread away in more than 80
countries. Scientists directed their efforts toward viral polymerase in attempt to find inhibitors …
countries. Scientists directed their efforts toward viral polymerase in attempt to find inhibitors …
Potential antiviral peptides targeting the SARS-CoV-2 spike protein
Background The coronavirus disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection became an international pandemic and created a …
coronavirus 2 (SARS-CoV-2) infection became an international pandemic and created a …