[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
Toll-like receptor stimulation in cancer: a pro-and anti-tumor double-edged sword
M Dajon, K Iribarren, I Cremer - Immunobiology, 2017 - Elsevier
Toll-like receptors (TLRs) are a family of transmembrane receptors that recognize various
pathogen-and damage-associated molecular pattern molecules playing an important role in …
pathogen-and damage-associated molecular pattern molecules playing an important role in …
The role of toll‐like receptor 4 (TLR4) in cancer progression: A possible therapeutic target?
The toll‐like receptor (TLR) family consists of vital receptors responsible for pattern
recognition in innate immunity, making them the core proteins involved in pathogen …
recognition in innate immunity, making them the core proteins involved in pathogen …
Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms
Strong epidemiological data indicate that chemotherapy-induced gut toxicity and pain occur
in parallel, indicating common underlying mechanisms. We have recently outlined evidence …
in parallel, indicating common underlying mechanisms. We have recently outlined evidence …
Toll-like receptor-induced cytokines as immunotherapeutic targets in cancers and autoimmune diseases
Immune cells of the myeloid and lymphoid lineages express Toll-like receptors (TLRs) to
recognize pathogenic components or cellular debris and activate the immune system …
recognize pathogenic components or cellular debris and activate the immune system …
Lipopolysaccharide (LPS) enhances prostate cancer metastasis potentially through NF‐κB activation and recurrent dexamethasone administration fails to suppress it …
Background Previous studies have shown the effect of bacterial lipopolysaccharide (LPS) on
enhanced cancer cells' growth and metastasis. However, the effect of LPS on prostate …
enhanced cancer cells' growth and metastasis. However, the effect of LPS on prostate …
Fecal Akkermansia muciniphila is associated with body composition and microbiota diversity in overweight and obese women with breast cancer participating in a …
AD Fruge, W Van der Pol, LQ Rogers… - Journal of the Academy …, 2020 - Elsevier
Background Akkermansia muciniphila (AM) is a gram-negative, mucin-degrading bacteria
inhabiting the gastrointestinal tract associated with host phenotypes and disease states …
inhabiting the gastrointestinal tract associated with host phenotypes and disease states …
The microbiome and prostate cancer risk
KM Wheeler, MA Liss - Current urology reports, 2019 - Springer
Abstract Purpose of the Review There is an abundance of evidence that the human
microbiome plays an important and nuanced role in controlling human metabolism …
microbiome plays an important and nuanced role in controlling human metabolism …
Escherichia coli, a common constituent of benign prostate hyperplasia‐associated microbiota induces inflammation and DNA damage in prostate epithelial cells
Background The role of microbiota in the pathophysiology of benign prostate hyperplasia
(BPH), especially in creating an inflammatory milieu may not be avoided. The major …
(BPH), especially in creating an inflammatory milieu may not be avoided. The major …
[HTML][HTML] Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism
J Hu, J Xu, X Feng, Y Li, F Hua, G Xu - Frontiers in Cell and …, 2021 - frontiersin.org
Previous studies have revealed the relationship between toll-like receptor 4 (TLR4)
polymorphisms and cancer susceptibility. However, the relationship between TLR4 and …
polymorphisms and cancer susceptibility. However, the relationship between TLR4 and …