Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …

Every year, cancer is responsible for millions of deaths worldwide and, even though much
progress has been achieved in medicine, there are still many issues that must be addressed …

The RNA interference (RNAi) pathway regulates mRNA stability and translation in nearly all
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …

Genome editing offers promising solutions to genetic disorders by editing DNA sequences
or modulating gene expression. The clustered regularly interspaced short palindromic …

Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …

Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Pancreatic cancer is one of the deadliest human cancers, whose progression is highly
dependent on the nervous microenvironment. The suppression of gene expression of nerve …

Gene therapy is a promising strategy for specific treatment of numerous gene-associated
human diseases by intentionally altering the gene expression in pathological cells. A …

Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …