Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …

The peptidoglycan sacculus is a net-like polymer that surrounds the cytoplasmic membrane
in most bacteria. It is essential to maintain the bacterial cell shape and protect from turgor …

Peptidoglycan (PG) is a cross-linked, meshlike scaffold endowed with the strength to
withstand the internal pressure of bacteria. Bacteria are known to heavily remodel their …

Introduction Mycobacteria assemble a complex cell wall with cross-linked peptidoglycan
(PG) which plays an essential role in maintenance of cell wall integrity and tolerance to …

The bacterial peptidoglycan layer forms a complex mesh-like structure that surrounds the
cell, imparting rigidity to withstand cytoplasmic turgor and the ability to tolerate stress. As …

Peptidoglycan (PG) is an essential component of the cell envelope, maintaining bacterial
cell shape and protecting it from bursting due to turgor pressure. The monoderm bacterium …

Cell walls are barriers found in almost all known bacterial cells. These structures establish a
controlled interface between the external environment and vital cellular components. A …

The general lack of permeability of small molecules observed for Mycobacterium
tuberculosis (Mtb) is most ascribed to its unique cell envelope. More specifically, the outer …

Serving as an exoskeletal scaffold, peptidoglycan is a polymeric macromolecule that is
essential and conserved across all bacteria, yet is absent in mammalian cells; this has made …

Superbugs' resistivity against available natural products has become an alarming global
threat, causing a rapid deterioration in public health and claiming tens of thousands of lives …