Colorectal cancer had a low incidence several decades ago. However, it has become a
predominant cancer and now accounts for approximately 10% of cancer-related mortality in …

Despite innovative advancements, distally located rectal cancer remains a critical disease of
challenging management. The crucial location of the tumor predisposes it to a …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

Objective: The aim of the study was to confirm the noninferiority of mesorectal excision (ME)
alone to ME with lateral lymph node dissection (LLND) in terms of efficacy. Background …

The risk increases with age. Median age at diagnosis is about 70 years or slightly older in
most European countries. The literature on risk factors for colorectal cancer is extensive. Diet …

Abstract Background Japan Clinical Oncology Group (JCOG) 0212 (ClinicalTrials. gov
NCT00190541) was a non-inferiority phase III trial of patients with clinical stage II–III rectal …

Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic
lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with …

BACKGROUND: Despite the use of neoadjuvant chemoradiation and total mesorectal
excision for rectal cancer, lateral pelvic lymph node recurrence is still an important problem …

BACKGROUND: Oncological outcomes of lateral pelvic lymph node metastasis in rectal
cancer treated with preoperative chemoradiotherapy remain to be elucidated. OBJECTIVE …

Background: Laparoscopic surgery for rectal cancer is widely performed all over the world
and several randomized controlled trials have been reported. However, the usefulness of …