Identification, evaluation, and management of children with autism spectrum disorder

SL Hyman, SE Levy, SM Myers, DZ Kuo, S Apkon… - …, 2020 - publications.aap.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with reported
prevalence in the United States of 1 in 59 children (approximately 1.7%). Core deficits are …

[HTML][HTML] Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation

H Hodges, C Fealko, N Soares - Translational pediatrics, 2020 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social communication and the presence of restricted interests and repetitive behaviors …

Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

X Zhou, P Feliciano, C Shu, T Wang, I Astrovskaya… - Nature …, 2022 - nature.com
To capture the full spectrum of genetic risk for autism, we performed a two-stage analysis of
rare de novo and inherited coding variants in 42,607 autism cases, including 35,130 new …

Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

The contribution of environmental exposure to the etiology of autism spectrum disorder

S Bölte, S Girdler, PB Marschik - Cellular and Molecular Life Sciences, 2019 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their …

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Association of genetic and environmental factors with autism in a 5-country cohort

D Bai, BHK Yip, GC Windham, A Sourander… - JAMA …, 2019 - jamanetwork.com
Importance The origins and development of autism spectrum disorder (ASD) remain
unresolved. No individual-level study has provided estimates of additive genetic, maternal …

Sensory perception in autism

CE Robertson, S Baron-Cohen - Nature Reviews Neuroscience, 2017 - nature.com
Autism is a complex neurodevelopmental condition, and little is known about its
neurobiology. Much of autism research has focused on the social, communication and …

An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity

E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …