The transcription factor NRF2 (nuclear factor erythroid 2‐related factor 2) triggers the first
line of homeostatic responses against a plethora of environmental or endogenous …

Abstract Systems medicine has a mechanism-based rather than a symptom-or organ-based
approach to disease and identifies therapeutic targets in a nonhypothesis-driven manner. In …

Abstract The Nrf2/Keap1 pathway is an important signaling cascade responsible for the
resistance of oxidative damage induced by exogenous chemicals. It maintains the redox …

The transcription factor nuclear factor erythroid 2 (NF-E2)-related factor 2 (NRF2) is a central
regulator of redox, metabolic, and protein homeostasis that intersects with many other …

Abstract The Keap1–Nrf2–ARE ((Kelch‐like ECH‐Associating protein 1) nuclear factor
erythroid 2 related factor 2‐antioxidant response element) pathway is one of the most …

Since ochratoxin A (OTA) was discovered, it has been ubiquitous as a natural contaminant
of moldy food and feed. The multiple toxic effects of OTA are a real threat for human beings …

Ochratoxin A (OTA) is a widespread mycotoxin commonly found as a corn contaminant. It
has been shown to be nephrotoxic, hepatotoxic, teratogenic and immunotoxic to several …

Ochratoxins (OTs) are a group of mycotoxins produced by Aspergillus and Penicillium spp.
which are ubiquitous. They infect the crops during pre-and post-harvest conditions and …

Ochratoxins are a group of mycotoxins produced by a variety of moulds. Ochratoxin A (OTA),
the most prominent member of this toxin family, was first described by van der Merwe et al. in …

Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health
risks. The focus of the present review is on the molecular and cellular interactions of OTA. In …