MicroRNAs in kidney physiology and disease
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression.
They have important roles during kidney development, homeostasis and disease. In …
They have important roles during kidney development, homeostasis and disease. In …
In-silico algorithms for the screening of possible microRNA binding sites and their interactions
H Dweep, C Sticht, N Gretz - Current genomics, 2013 - ingentaconnect.com
MicroRNAs (miRNAs) comprise a recently discovered class of small, non-coding RNA
molecules of 21-25 nucleotides in length that regulate the gene expression by base-pairing …
molecules of 21-25 nucleotides in length that regulate the gene expression by base-pairing …
miRWalk database for miRNA–target interactions
H Dweep, N Gretz, C Sticht - RNA mapping: methods and protocols, 2014 - Springer
Abstract miRWalk (http://mirwalk. uni-hd. de/) is a publicly available comprehensive
resource, hosting the predicted as well as the experimentally validated microRNA (miRNA) …
resource, hosting the predicted as well as the experimentally validated microRNA (miRNA) …
MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis
Transcriptional dysregulation has long been recognized as central to the pathogenesis of
Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post …
Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post …
miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy
MF Hennino, D Buob, C Van der Hauwaert… - Scientific reports, 2016 - nature.com
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis, whose prognosis
is highly variable. Interstitial fibrosis is a strong independent prognosis factor. Among …
is highly variable. Interstitial fibrosis is a strong independent prognosis factor. Among …
MicroRNA-21 aggravates cyst growth in a model of polycystic kidney disease
R Lakhia, S Hajarnis, D Williams… - Journal of the …, 2016 - journals.lww.com
Autosomal dominant polycystic kidney disease (ADPKD), one of the most common
monogenetic disorders, is characterized by kidney failure caused by bilateral renal cyst …
monogenetic disorders, is characterized by kidney failure caused by bilateral renal cyst …
Molecular pathways and therapies in autosomal-dominant polycystic kidney disease
T Saigusa, PD Bell - Physiology, 2015 - journals.physiology.org
Autosomal-dominant polycystic kidney disease (ADPKD) is the most prevalent inherited
renal disease, characterized by multiple cysts that can eventually lead to kidney failure …
renal disease, characterized by multiple cysts that can eventually lead to kidney failure …
Global microRNA profiling in human urinary exosomes reveals novel disease biomarkers and cellular pathways for autosomal dominant polycystic kidney disease
TA Magayr, X Song, AJ Streets, L Vergoz, L Chang… - Kidney international, 2020 - Elsevier
MicroRNAs (miRNAs) play an important role in regulating gene expression in health and
disease but their role in modifying disease expression in Autosomal Dominant Polycystic …
disease but their role in modifying disease expression in Autosomal Dominant Polycystic …
Ochratoxin A induced early hepatotoxicity: new mechanistic insights from microRNA, mRNA and proteomic profiling studies
The mycotoxin ochratoxin A (OTA) is found widely in agricultural commodities. OTA can
induce various toxicities. In this study, rats were gavaged with OTA for different weeks. Then …
induce various toxicities. In this study, rats were gavaged with OTA for different weeks. Then …
Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells
Acute kidney injury (AKI) is characterized by tubular cell death and interstitial inflammation.
TWEAK promotes experimental kidney injury and activates the transcription factor NF-κB, a …
TWEAK promotes experimental kidney injury and activates the transcription factor NF-κB, a …