The Eph receptor tyrosine kinases and their ephrin ligands have intriguing expression
patterns in cancer cells and tumour blood vessels, which suggest important roles for their …

Simple Summary The Eph receptor family is implicated in both tumour promotion and
suppression, depending on the tissue-specific context of available receptor interactions with …

To reveal molecular drivers of glioma invasion, two distinct glioblastoma (GBM) cell
phenotypes (invading cells and tumor core cells) were collected from 19 GBM specimens …

Cancer invasiveness plays a major role in the mortality of patients with solid tumors, and
deregulated cell adhesion and migration are suspected to drive invasive behavior. Since …

Purpose: Loss of EPHB6 receptor tyrosine kinase expression in early-stage non–small cell
lung carcinoma (NSCLC) is associated with the subsequent development of distant …

Abstract Background Ephrin (Eph) receptors are frequently overexpressed in a wide variety
of human malignant tumors, being associated with tumor growth, invasion, metastasis and …

The erythropoietin-producing hepatocellular (Eph) receptors comprise the largest family of
receptor tyrosine kinases (RTKs). Initially regarded as axon-guidance and tissue-patterning …

During development and regeneration, directed migration of cells, including neural crest
cells, endothelial cells, axonal growth cones and many types of adult stem cells, to specific …

Eph receptor tyrosine kinases and their ligands, ephrins, are membrane proteins
coordinating a wide range of biological functions both in developing embryos and in adult …

The Eph receptor tyrosine kinases make up an important family of signal transduction
molecules that control many cellular processes, including cell adhesion and movement, cell …