Update on the mechanisms and roles of high‐frequency oscillations in seizures and epileptic disorders
High‐frequency oscillations (HFO s) are a type of brain activity that is recorded from brain
regions capable of generating seizures. Because of the close association of HFO s with …
regions capable of generating seizures. Because of the close association of HFO s with …
Multiscale recordings reveal the dynamic spatial structure of human seizures
The cellular activity underlying human focal seizures, and its relationship to key signatures
in the EEG recordings used for therapeutic purposes, has not been well characterized …
in the EEG recordings used for therapeutic purposes, has not been well characterized …
Semi-supervised automatic seizure detection using personalized anomaly detecting variational autoencoder with behind-the-ear EEG
Abstract Background and Objective Epilepsy is one of the most common neurologic
diseases worldwide, and 30% of the patients live with uncontrolled seizures. For the safety …
diseases worldwide, and 30% of the patients live with uncontrolled seizures. For the safety …
Role of inhibitory control in modulating focal seizure spread
Focal seizure propagation is classically thought to be spatially contiguous. However,
distribution of seizures through a large-scale epileptic network has been theorized. Here, we …
distribution of seizures through a large-scale epileptic network has been theorized. Here, we …
Cross-scale effects of neural interactions during human neocortical seizure activity
Small-scale neuronal networks may impose widespread effects on large network dynamics.
To unravel this relationship, we analyzed eight multiscale recordings of spontaneous …
To unravel this relationship, we analyzed eight multiscale recordings of spontaneous …
Interneurons and principal cell firing in human limbic areas at focal seizure onset
Since the discovery of inhibitory post-synaptic potentials (IPSPs) by Sir John Eccles in 1952,
and the identification of GABA (gamma-Aminobutyric acid) as the major inhibitory …
and the identification of GABA (gamma-Aminobutyric acid) as the major inhibitory …
Cell-type specific and multiscale dynamics of human focal seizures in limbic structures
AH Agopyan-Miu, EM Merricks, EH Smith… - Brain, 2023 - academic.oup.com
The relationship between clinically accessible epileptic biomarkers and neuronal activity
underlying the transition to seizure is complex, potentially leading to imprecise delineation of …
underlying the transition to seizure is complex, potentially leading to imprecise delineation of …
Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures
Loss of consciousness is a hallmark of many epileptic seizures and carries risks of serious
injury and sudden death. While cortical sleep-like activities accompany loss of …
injury and sudden death. While cortical sleep-like activities accompany loss of …
Activation of nicotinamide adenine dinucleotide phosphate oxidase is the primary trigger of epileptic seizures in rodent models
A Malkov, AI Ivanov, A Latyshkova… - Annals of …, 2019 - Wiley Online Library
Objective Despite decades of epilepsy research, 30% of focal epilepsies remain resistant to
antiseizure drugs, with effective drug development impeded by lack of understanding on …
antiseizure drugs, with effective drug development impeded by lack of understanding on …
A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings
ZJ Waldman, S Shimamoto, I Song, I Orosz… - Clinical …, 2018 - Elsevier
Objective To develop a reliable software method using a topographic analysis of time-
frequency plots to distinguish ripple (80–200 Hz) oscillations that are often associated with …
frequency plots to distinguish ripple (80–200 Hz) oscillations that are often associated with …