The cryoglobulinaemias
M Ramos-Casals, JH Stone, MC Cid, X Bosch - The Lancet, 2012 - thelancet.com
Cryoglobulins are immunoglobulins that precipitate in vitro at temperatures less than 37° C
and produce organ damage through two main pathways: vascular sludging (hyperviscosity …
and produce organ damage through two main pathways: vascular sludging (hyperviscosity …
Cryoglobulinaemia
D Roccatello, D Saadoun, M Ramos-Casals… - Nature reviews Disease …, 2018 - nature.com
Cryoglobulinaemia refers to the serum presence of cryoglobulins, which are defined as
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: the multiethnic cohort
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV)
infection. The mechanism of HCV‐related lymphoproliferative disorders is not fully …
infection. The mechanism of HCV‐related lymphoproliferative disorders is not fully …
Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes
Membrane lipids and proteins are non-randomly distributed and are unable to diffuse freely
in the plane of the membrane. This is because of multiple constraints imposed both by the …
in the plane of the membrane. This is because of multiple constraints imposed both by the …
The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
An understanding of how broadly neutralizing activity develops in HIV-1-infected individuals
is needed to guide vaccine design and immunization strategies. Here we used a large panel …
is needed to guide vaccine design and immunization strategies. Here we used a large panel …
Hepatitis viruses and non-Hodgkin lymphoma: epidemiology, mechanisms of tumorigenesis, and therapeutic opportunities
F Marcucci, A Mele - Blood, The Journal of the American …, 2011 - ashpublications.org
Over the past 2 decades considerable evidence has accumulated on the association
between hepatitis C virus (HCV) and hepatitis B virus (HBV) and several hematologic …
between hepatitis C virus (HCV) and hepatitis B virus (HBV) and several hematologic …
[HTML][HTML] Hepatitis C-associated B-cell non-Hodgkin lymphomas. Epidemiology, molecular signature and clinical management
J Peveling-Oberhag, L Arcaini, ML Hansmann… - Journal of …, 2013 - Elsevier
There is ample epidemiologic evidence for an association of chronic hepatitis C virus (HCV)
infection with B-cell non-Hodgkin lymphoma (B-NHL). B-NHL subtypes most frequently …
infection with B-cell non-Hodgkin lymphoma (B-NHL). B-NHL subtypes most frequently …
Flying under the radar: the immunobiology of hepatitis C
LB Dustin, CM Rice - Annu. Rev. Immunol., 2007 - annualreviews.org
The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
[HTML][HTML] Hepatitis C virus–induced cryoglobulinemia
ED Charles, LB Dustin - Kidney international, 2009 - Elsevier
In this review we discuss the clinical manifestations, pathogenesis, and treatment of hepatitis
C virus (HCV)–related cryoglobulinemia. HCV is a major cause of liver-related morbidity and …
C virus (HCV)–related cryoglobulinemia. HCV is a major cause of liver-related morbidity and …
[HTML][HTML] The long and winding road leading to the identification of the hepatitis C virus
M Houghton - Journal of hepatology, 2009 - Elsevier
This review describes work conducted largely in my laboratory at the Chiron Corporation
between 1982 and 1989 that led to the identification of the hepatitis C virus (HCV). Key …
between 1982 and 1989 that led to the identification of the hepatitis C virus (HCV). Key …