Naturally occurring PCSK9 inhibitors

MP Adorni, F Zimetti, MG Lupo, M Ruscica, N Ferri - Nutrients, 2020 - mdpi.com
Genetic, epidemiological and pharmacological data have led to the conclusion that
antagonizing or inhibiting Proprotein convertase subtilisin/kexin type 9 (PCSK9) reduces …

Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis

K Feng, X Zhu, G Liu, Q Kan, T Chen, Y Chen, Y Cao - Food & function, 2020 - pubs.rsc.org
Citrus peel essential oil (CPEO) contains abundant volatile compounds and exhibits
fragrance properties and beneficial pharmacological effects on humans. Herein, we aimed …

Gamma-Irradiation-Induced Degradation of the Water-Soluble Polysaccharide from Auricularia polytricha and Its Anti-Hypercholesterolemic Activity

P Li, C Xiong, W Huang - Molecules, 2022 - mdpi.com
The water-soluble polysaccharides (APPs) isolated from the edible mushroom Auricularia
polytricha were irradiated by γ-ray at doses of 10, 100, and 1000 kGy. The effect of gamma …

Anticancer activity and mechanism of total saponins from the residual seed cake of Camellia oleifera Abel. in hepatoma-22 tumor-bearing mice

D Wang, R Huo, C Cui, Q Gao, J Zong, Y Wang… - Food & function, 2019 - pubs.rsc.org
We have previously demonstrated that several new saponins from the seed cake of
Camellia oleifera Abel. exhibited antiproliferative activity against human tumor cells in vitro …

Edible Bird's Nest Effectively Attenuates Atherosclerosis through Modulation of Cholesterol Metabolism via Activation of PPARγ/LXRα Signaling Pathway In Vivo

NN Mohamad Nasir… - Journal of Food …, 2023 - Wiley Online Library
Atherosclerosis is the underlying cause of the majority of cardiovascular diseases (CVDs)
due to high‐cholesterol deposition in the aorta, resulting in hardening and narrowing of …

Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways

N Irshad, A Khan, FA Shah, H Nadeem… - Fundamental & …, 2021 - Wiley Online Library
Hyperlipidemia is worth‐mentioning risk factor in quickly expanding atherosclerosis,
myocardial infarction, and stroke. This study attempted to determine effectiveness of …

Antihypertensive Potential of Japanese Quail (Couturnix Couturnix Japonica) Egg Yolk Oil (QEYO) in Sprague Dawley Rats

MS Ismaila, SO Balogun-Raji, F Hamza, UB Sadiya… - Biology, 2024 - mdpi.com
Simple Summary Quail eggs have been reported as a nutraceutical in developed and
developing countries. However, there are few documented reports on the effect of quail egg …

Defatted Kenaf (Hibiscus cannabinus L.) Seed Meal and Its Phenolic‐Saponin‐Rich Extract Protect Hypercholesterolemic Rats against Oxidative Stress and Systemic …

KW Chan, M Ismail, N Mohd Esa… - Oxidative medicine …, 2018 - Wiley Online Library
The present study aimed to investigate the antioxidant and anti‐inflammatory properties of
defatted kenaf seed meal (DKSM) and its phenolic‐saponin‐rich extract (PSRE) in …

Coumaric and cinnamic acids in food

N Poklar Ulrih, I Prislan, B Cigić - Handbook of Dietary Phytochemicals, 2021 - Springer
Cinnamic and coumaric acids belong to the large family of phenylpropanoids with C6-C3
skeleton. Main biosynthetic route involves deamination of phenylalanine into trans-cinnamic …

[PDF][PDF] Induction of Hypercholesterolemia in Rodents Based on Different Dietary Requirements: A Systematic Review.

A Hassan, Z Abdullah, S Safuan - Malaysian Journal of …, 2023 - medic.upm.edu.my
ABSTRACT Introduction: Cardiovascular diseases (CVDs) are the most common cause of
death around the world. CVDs claimed the lives of 17.9 million individuals worldwide in …