[HTML][HTML] Botulinum toxin in the management of children with cerebral palsy

I Multani, J Manji, T Hastings-Ison, A Khot, K Graham - Pediatric Drugs, 2019 - Springer
During the past 25 years, botulinum toxin type A (BoNT-A) has become the most widely used
medical intervention in children with cerebral palsy. In this review we consider the gaps in …

Spasticity and its contribution to hypertonia in cerebral palsy

L Bar-On, G Molenaers, E Aertbeliën… - BioMed research …, 2015 - Wiley Online Library
Spasticity is considered an important neural contributor to muscle hypertonia in children with
cerebral palsy (CP). It is most often treated with antispasticity medication, such as Botulinum …

[HTML][HTML] Reliability of Ashworth and Modified Ashworth scales in children with spastic cerebral palsy

A Mutlu, A Livanelioglu, MK Gunel - BMC musculoskeletal disorders, 2008 - Springer
Background Measurement of spasticity is a difficult and unresolved problem, partly due to its
complexity and the fact that there are many factors involved. In the assessment of spasticity …

Practice Parameter: Pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review) Report of the Quality Standards …

MR Delgado, D Hirtz, M Aisen, S Ashwal, DL Fehlings… - Neurology, 2010 - AAN Enterprises
Objective: To evaluate published evidence of efficacy and safety of pharmacologic
treatments for childhood spasticity due to cerebral palsy. Methods: A multidisciplinary panel …

Spastic hypertonia and movement disorders: pathophysiology, clinical presentation, and quantification

G Sheean, JR McGuire - PM&R, 2009 - Elsevier
A delayed consequence of a lesion affecting the upper motor neuron pathways is the
appearance of some forms of motor overactivity, including spasticity. Many of these are …

Interrater reliability of the Modified Modified Ashworth Scale (MMAS) for patients with wrist flexor muscle spasticity

S Naghdi, N Nakhostin Ansari, S Azarnia… - … Theory and practice, 2008 - Taylor & Francis
The measurement of spasticity is part of the neurological examination of patients with
disorders of the central nervous system. Recently, the Modified Modified Ashworth Scale …

A neurophysiological and clinical study of Brunnstrom recovery stages in the upper limb following stroke

S Naghdi, NN Ansari, K Mansouri, S Hasson - Brain injury, 2010 - Taylor & Francis
Primary objective: To determine the extent to which the Brunnstrom recovery stages of upper
limb in hemiparetic stroke patients are correlated to neurophysiological measures and the …

European consensus on the concepts and measurement of the pathophysiological neuromuscular responses to passive muscle stretch

JC van den Noort, L Bar‐On… - European journal of …, 2017 - Wiley Online Library
Background and purpose To support clinical decision‐making in central neurological
disorders, a physical examination is used to assess responses to passive muscle stretch …

[PDF][PDF] Measurement of lower-limb muscle spasticity: Intrarater reliability of Modified Modified Ashworth Scale

N Ghotbi, NN Ansari, S Naghdi… - J Rehabil Res …, 2011 - rehab.research.va.gov
The Modified Modified Ashworth Scale (MMAS) is a clinical instrument for measuring
spasticity. Few studies have been performed on the reliability of the MMAS. The aim of the …

Pharmacological management of spasticity in multiple sclerosis: systematic review and consensus paper

S Otero-Romero, J Sastre-Garriga… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background and objectives: Treatment of spasticity poses a major challenge given the
complex clinical presentation and variable efficacy and safety profiles of available drugs. We …