Spinal cord stimulation: clinical efficacy and potential mechanisms
AD Sdrulla, Y Guan, SN Raja - Pain Practice, 2018 - Wiley Online Library
Spinal cord stimulation (SCS) is a minimally invasive therapy used for the treatment of
chronic neuropathic pain. SCS is a safe and effective alternative to medications such as …
chronic neuropathic pain. SCS is a safe and effective alternative to medications such as …
Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults
MI Johnson, MR Mulvey… - Cochrane Database of …, 2015 - cochranelibrary.com
Background This is the first update of a Cochrane review published in Issue 5, 2010 on
transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain …
transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain …
Astrocytes contribute to pain gating in the spinal cord
Various pain therapies have been developed on the basis of the gate control theory of pain,
which postulates that nonpainful sensory inputs mediated by large-diameter afferent fibers …
which postulates that nonpainful sensory inputs mediated by large-diameter afferent fibers …
[HTML][HTML] Spinal cord stimulation in chronic neuropathic pain: mechanisms of action, new locations, new paradigms
EA Joosten, G Franken - Pain, 2020 - journals.lww.com
Neuropathic pain is a complex, heterogeneous disorder that affects approximately 8% of the
total adult human population and comes with significant burden for both the patient and …
total adult human population and comes with significant burden for both the patient and …
Spinal cord stimulation for treating chronic pain: reviewing preclinical and clinical data on paresthesia-free high-frequency therapy
K Chakravarthy, H Richter, PJ Christo… - … : Technology at the …, 2018 - Elsevier
Background Traditional spinal cord stimulation (SCS) requires that paresthesia overlaps
chronic painful areas. However, the new paradigm high-frequency SCS (HF-SCS) does not …
chronic painful areas. However, the new paradigm high-frequency SCS (HF-SCS) does not …
[PDF][PDF] Absence of paresthesia during high-rate spinal cord stimulation reveals importance of synchrony for sensations evoked by electrical stimulation
B Sagalajev, T Zhang, N Abdollahi, N Yousefpour… - Neuron, 2024 - cell.com
Electrically activating mechanoreceptive afferents inhibits pain. However, paresthesia
evoked by spinal cord stimulation (SCS) at 40–60 Hz becomes uncomfortable at high pulse …
evoked by spinal cord stimulation (SCS) at 40–60 Hz becomes uncomfortable at high pulse …
[HTML][HTML] Neuromorphic hardware for somatosensory neuroprostheses
In individuals with sensory-motor impairments, missing limb functions can be restored using
neuroprosthetic devices that directly interface with the nervous system. However, restoring …
neuroprosthetic devices that directly interface with the nervous system. However, restoring …
Peripherally induced reconditioning of the central nervous system: a proposed mechanistic theory for sustained relief of chronic pain with percutaneous peripheral …
TR Deer, S Eldabe, SM Falowski… - Journal of Pain …, 2021 - Taylor & Francis
Peripheral nerve stimulation (PNS) is an effective tool for the treatment of chronic pain,
although its efficacy and utilization have previously been significantly limited by technology …
although its efficacy and utilization have previously been significantly limited by technology …
Surround inhibition mediates pain relief by low amplitude spinal cord stimulation: modeling and measurement
Abstract Low-frequency (< 200 Hz), subperception spinal cord stimulation (SCS) is a novel
modality demonstrating therapeutic efficacy for treating chronic neuropathic pain. When …
modality demonstrating therapeutic efficacy for treating chronic neuropathic pain. When …
In vivo measurements reveal that both low-and high-frequency spinal cord stimulation heterogeneously modulate superficial dorsal horn neurons
Current sub-perception spinal cord stimulation (SCS) is characterized by the use of high-
frequency pulses to achieve paresthesia-free analgesic effects. High-frequency SCS …
frequency pulses to achieve paresthesia-free analgesic effects. High-frequency SCS …