Regenerative medicine as applied to general surgery
The present review illustrates the state of the art of regenerative medicine (RM) as applied to
surgical diseases and demonstrates that this field has the potential to address some of the …
surgical diseases and demonstrates that this field has the potential to address some of the …
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling
Z Wang, L Wang, R Jiang, C Li, X Chen, H Xiao… - Free Radical Biology …, 2021 - Elsevier
Senescence limits the characteristics and functionality of mesenchymal stem cells (MSCs),
thereby severely restricting their application in tissue engineering. Here, we investigated …
thereby severely restricting their application in tissue engineering. Here, we investigated …
Cell therapy in muscular dystrophies: many promises in mice and dogs, few facts in patients
D Skuk, JP Tremblay - Expert opinion on biological therapy, 2015 - Taylor & Francis
Introduction: Muscular dystrophies (MDs) are genetic diseases that produce progressive
loss of skeletal muscle fibers. Cell therapy (CT) is an experimental approach to treat MD …
loss of skeletal muscle fibers. Cell therapy (CT) is an experimental approach to treat MD …
Restoration of skeletal muscle defects with adult human cells delivered on fibrin microthreads
RL Page, C Malcuit, L Vilner, I Vojtic… - … Engineering Part A, 2011 - liebertpub.com
Large-scale musculoskeletal wounds, such as those seen in trauma injuries, present poor
functional healing prognoses. In severe trauma, when the native tissue architecture is …
functional healing prognoses. In severe trauma, when the native tissue architecture is …
Preconditioning of bone marrow-derived mesenchymal stem cells with N-acetyl-L-cysteine enhances bone regeneration via reinforced resistance to oxidative stress
Oxidative stress on transplanted bone marrow-derived mesenchymal stem cells (BMSCs)
during acute inflammation is a critical issue in cell therapies. N-acetyl-L cysteine (NAC) …
during acute inflammation is a critical issue in cell therapies. N-acetyl-L cysteine (NAC) …
Isolation and characterization of porcine adult muscle‐derived progenitor cells
KJ Wilschut, S Jaksani… - Journal of cellular …, 2008 - Wiley Online Library
Here, we report the isolation of progenitor cells from pig skeletal muscle tissue fragments.
Muscle progenitor cells were stimulated to migrate from protease-digested tissue fragments …
Muscle progenitor cells were stimulated to migrate from protease-digested tissue fragments …
A simplified but robust method for the isolation of avian and mammalian muscle satellite cells
B Baquero-Perez, SV Kuchipudi, RK Nelli, KC Chang - BMC Cell Biology, 2012 - Springer
Background Current methods of isolation of muscle satellite cells from different animal
species are highly variable making inter-species comparisons problematic. This variation …
species are highly variable making inter-species comparisons problematic. This variation …
Autologous bone marrow-derived cells enhance muscle strength following skeletal muscle crush injury in rats
G Matziolis, T Winkler, K Schaser, M Wiemann… - Tissue …, 2006 - liebertpub.com
Insufficient post-traumatic skeletal muscle regeneration with consecutive functional
deficiency continues to be a serious problem in orthopedic and trauma surgery …
deficiency continues to be a serious problem in orthopedic and trauma surgery …
Intramuscular transplantation of human postnatal myoblasts generates functional donor-derived satellite cells
D Skuk, M Paradis, M Goulet, P Chapdelaine… - Molecular Therapy, 2010 - cell.com
Myogenic cell transplantation is an experimental approach for the treatment of myopathies.
In this approach, transplanted cells need to fuse with pre-existing myofibers, form new …
In this approach, transplanted cells need to fuse with pre-existing myofibers, form new …
Intramuscular cell transplantation as a potential treatment of myopathies: clinical and preclinical relevant data
D Skuk, JP Tremblay - Expert opinion on biological therapy, 2011 - Taylor & Francis
Introduction: Myopathies produce deficits in skeletal muscle function and, in some cases,
literally progressive loss of skeletal muscles. The transplantation of cells able to differentiate …
literally progressive loss of skeletal muscles. The transplantation of cells able to differentiate …