Metastasis consists of hallmark events, including Epithelial-Mesenchymal Transition (EMT),
angiogenesis, initiation of inflammatory tumor microenvironment, and malfunctions in …

Autophagy is a self-degradative cellular process, involved in stress response such as
starvation, hypoxia, and oxidative stress. This mechanism balances macro-molecule …

Aims This study aims at investigating the role of a neighbor long non-coding RNA (lncRNA)
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …

The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal
carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH …

Hedgehog (Hh) pathway controls complex developmental processes in vertebrates.
Abnormal activation of Hh pathway is responsible for tumorigenesis and maintenance of …

Autophagy is a process of cell self-renewal that is dependent on the degradation of the
cytoplasmic proteins or organelles of lysosomes. Many diseases, such as metabolic …

The complicated stepwise lysosomal degradation process known as autophagy is in charge
of destroying and eliminating damaged organelles and defective cytoplasmic components …

Endothelial cell dysfunction plays an important role in cerebral ischemia-reperfusion (I/R)
injury. LncRNA Peg13 is reported to be down-regulated in brain microvascular endothelial …

Background LINC00346 has recently been reported to regulate the development of several
cancer types, but its biological functions and underlying mechanisms in lung …

The sonic hedgehog (Shh) pathway is highly activated in a variety of malignancies and
plays important roles in tumorigenesis, tumor growth, drug resistance, and metastasis. Our …