Glutamate receptors (GluRs) mediate most of the excitatory neurotransmission in the
mammalian central nervous system (CNS). In addition, they are involved in plastic changes …

Forty years of research into the function of l-glutamic acid as a neurotransmitter in the
vertebrate central nervous system (CNS) have uncovered a tremendous complexity in the …

The N-methyl-D-aspartate (NMDA) receptor subserves synaptic glutamate-induced
transmission and plasticity in central neurons. The yeast two-hybrid system was used to …

Rasmussen's encephalitis is a progressive childhood disease of unknown cause
characterized by severe epilepsy, hemiplegia, dementia, and inflammation of the brain …

Glutamate, the neurotransmitter at most excitatory synapses in the brain, activates a variety
of receptor subtypes that can broadly be divided into ionotropic (ligand-gated ion channels) …

▪ Abstract The quantity of neurotransmitter released into the synaptic cleft, the reliability with
which it is released, and the response of the postsynaptic cell to that transmitter all contribute …

Research on glutamatergic neurotransmission has focused mainly on the function of
presynaptic and postsynaptic neurons, leaving astrocytes with a secondary role only to …

Ionotropic glutamate receptors are composed of homomeric or heteromeric configurations of
glutamate receptor subunits. We have cloned a member of a novel class of the rat ionotropic …

This paper presents an overview of recent microscopic studies that have sought to define
how limbic circuitry may be altered in postmortem schizophrenic brain. The discussion is …

Glutamate receptors convey most of the fast excitatory transmission in the vertebrate central
nervous system (CNS). In addition, they appear to be crucially involved in plastic synaptic …