Biohybrid neural interfaces: improving the biological integration of neural implants
Implantable neural interfaces (NIs) have emerged in the clinic as outstanding tools for the
management of a variety of neurological conditions caused by trauma or disease. However …
management of a variety of neurological conditions caused by trauma or disease. However …
Bio-integrative design of the neural tissue-device interface
Highlights•Bio-integrative strategies promote neural tissue-device integration.•Surface
modifications camouflage the surface and promote neuron attachment.•Drug delivery …
modifications camouflage the surface and promote neuron attachment.•Drug delivery …
Neuroinflammatory gene expression analysis reveals pathways of interest as potential targets to improve the recording performance of intracortical microelectrodes
Intracortical microelectrodes are a critical component of brain-machine interface (BMI)
systems. The recording performance of intracortical microelectrodes used for both basic …
systems. The recording performance of intracortical microelectrodes used for both basic …
[HTML][HTML] The effect of a Mn (III) tetrakis (4-benzoic acid) porphyrin (MnTBAP) coating on the chronic recording performance of planar silicon intracortical microelectrode …
Intracortical microelectrode arrays (MEAs) are used to record neural activity. However, their
implantation initiates a neuroinflammatory cascade, involving the accumulation of reactive …
implantation initiates a neuroinflammatory cascade, involving the accumulation of reactive …
Differential expression of genes involved in the chronic response to intracortical microelectrodes
Abstract Brain-Machine Interface systems (BMIs) are clinically valuable devices that can
provide functional restoration for patients with spinal cord injury or improved integration for …
provide functional restoration for patients with spinal cord injury or improved integration for …
Spatiotemporal patterns of gene expression around implanted silicon electrode arrays
CH Thompson, A Saxena, N Heelan… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Intracortical brain interfaces are an ever evolving technology with growing
potential for clinical and research applications. The chronic tissue response to these devices …
potential for clinical and research applications. The chronic tissue response to these devices …
Antioxidant dimethyl fumarate temporarily but not chronically improves intracortical microelectrode performance
GF Hoeferlin, T Bajwa, H Olivares, J Zhang… - Micromachines, 2023 - mdpi.com
Intracortical microelectrode arrays (MEAs) can be used in a range of applications, from basic
neuroscience research to providing an intimate interface with the brain as part of a brain …
neuroscience research to providing an intimate interface with the brain as part of a brain …
Reactive Amine Functionalized Microelectrode Arrays Provide Short-Term Benefit but Long-Term Detriment to In Vivo Recording Performance
BS Sturgill, AG Hernandez-Reynoso… - ACS Applied Bio …, 2024 - ACS Publications
Intracortical microelectrode arrays (MEAs) are used for recording neural signals. However,
indwelling devices result in chronic neuroinflammation, which leads to decreased recording …
indwelling devices result in chronic neuroinflammation, which leads to decreased recording …
Development of a slow-degrading polymerized curcumin coating for intracortical microelectrodes
Intracortical microelectrodes are used with brain–computer interfaces to restore lost limb
function following nervous system injury. While promising, recording ability of intracortical …
function following nervous system injury. While promising, recording ability of intracortical …
[HTML][HTML] Therapeutic potential of targeting galectins–A biomaterials-focused perspective
Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …
glycan-binding proteins, have been described as key in immune cell homeostasis and …