Actinobacteria are well-recognised biosynthetic factories that produce an extensive
spectrum of secondary metabolites. Recent genomic insights seem to impact the exploitation …

Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial
biotechnology applications because of their metabolic versatility, ability to degrade a wide …

Actinomycetes are one of the most valuable sources of natural products with industrial and
medicinal importance. After more than half a century of exploitation, it has become …

Streptomyces is taken as an important resource for producing the most abundant antibiotics
and other bio-active natural products, which have been widely used in pharmaceutical and …

Covering: 2010 to 2020 Over the last few decades, Streptomyces have been extensively
investigated for their ability to produce diverse bioactive secondary metabolites. Recent …

The major reason behind the spread of antibiotic resistance genes (ARGs) is persistent
selective pressure in the environment encountered by bacteria. Genome plasticity plays a …

Microbial-derived natural products (NPs) and their derivative products are of great
importance and used widely in many fields, especially in pharmaceutical industries …

Valinomycin is a nonribosomal peptide that was discovered from Streptomyces in 1955.
Over the past more than six decades, it has received continuous attention due to its special …

Chromosomal integration of genes and pathways is of particular importance for large-scale
and long-term fermentation in industrial biotechnology. However, stable, multi-copy …

Streptomyces-based cell-free expression systems have been developed to meet the
demand for synthetic biology applications. However, protein yields from the previous …