Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …

Abstract Thiazolidinediones (TZDs) or Glitazones are an important class of insulin
sensitizers used in the treatment of Type 2 diabetes mellitus (T2DM). TZDs were reported for …

Abstract α-Glucosidase is a key enzyme in hydrolysis of carbohydrates to glucose and
located in the small intestine brush border. Inhibition of this enzyme delay the release of …

A novel series of quinazolinone-1, 2, 3-triazole hybrids 10a-p were designed, synthesized,
and evaluated for their in vitro α-glucosidase inhibitory activity leading to efficient anti …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Diabetes mellitus is a chronic and common metabolic disease that seriously endangers
human health. Hyperglycemia and long-term metabolic disorders in diabetes will cause …

A series of novel chalcone-triazole derivatives were synthesized and screened for in vitro
anticancer activity on the human cancer cell lines IMR32 (neuroblastoma), HepG2 …

Abstract A series of novel 1, 2, 3-triazole substituted N-phenyl nitrone derivatives 5a–e were
prepared in three steps starting from 1-substituted-1, 2, 3-triazole-4-carbaldehydes 2 via …

In this study, we designed and synthesized a number of novel pyrido [2, 3-d] pyrimidine-
thiazolidine-1, 2, 3-triazole derivatives and investigated them in vitro for their inhibitory …

Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a
privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into …