The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …

Serotonin has been implicated in the control of satiety for almost four decades. Historically,
the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

With over thirty different hormones identified as being produced in the gastrointestinal (GI)
tract, the gut has been described as 'the largest endocrine organ in the body'(Ann. Oncol …

Liver and serum metabolites of obese and lean mice fed on high fat or normal diets were
analyzed using ultraperformance liquid chromatography− quadrupole-time-of-flight mass …

Over the past 20 years, genetic studies have illuminated critical pathways in the
hypothalamus and brainstem mediating energy homeostasis, such as the melanocortin …

With their ever-growing prevalence, obesity and diabetes represent major health threats of
our society. Based on estimations by the World Health Organization, approximately 300 …

Energy and glucose homeostasis are regulated by central serotonin 2C receptors. These
receptors are attractive pharmacological targets for the treatment of obesity; however, the …

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

Carefully designed to balance coverage of theoretical and practical principles,
Fundamentals of Water Treatment Unit Processes delineates the principles that support …