Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?

C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …

Role of dietary nutrients in the modulation of gut microbiota: a narrative review

Q Yang, Q Liang, B Balakrishnan, DP Belobrajdic… - Nutrients, 2020 - mdpi.com
Understanding how dietary nutrients modulate the gut microbiome is of great interest for the
development of food products and eating patterns for combatting the global burden of non …

[HTML][HTML] Network analysis methods for studying microbial communities: A mini review

MS Matchado, M Lauber, S Reitmeier… - Computational and …, 2021 - Elsevier
Microorganisms including bacteria, fungi, viruses, protists and archaea live as communities
in complex and contiguous environments. They engage in numerous inter-and intra …

Colon carcinogenesis: the interplay between diet and gut microbiota

YL Loke, MT Chew, YF Ngeow, WWD Lim… - Frontiers in cellular and …, 2020 - frontiersin.org
Colorectal cancer (CRC) incidence increases yearly, and is three to four times higher in
developed countries compared to developing countries. The well-known risk factors have …

Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders

CA Alemao, KF Budden, HM Gomez, SF Rehman… - Allergy, 2021 - Wiley Online Library
The prevalence of chronic immune and metabolic disorders is increasing rapidly. In
particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive …

Iron deficiency, immunology, and colorectal cancer

O Phipps, MJ Brookes, HO Al-Hassi - Nutrition reviews, 2021 - academic.oup.com
Excessive gut luminal iron contributes to the initiation and progression of colorectal cancer.
However, emerging evidence suggests that reduced iron intake and low systemic iron levels …

[HTML][HTML] Protective effect of curcumin on ochratoxin A–induced liver oxidative injury in duck is mediated by modulating lipid metabolism and the intestinal microbiota

SS Zhai, D Ruan, YW Zhu, MC Li, H Ye, WC Wang… - Poultry Science, 2020 - Elsevier
Curcumin has antioxidant functions, regulates the intestinal microbial composition, and
alleviates mycotoxin toxicity. The present study aimed to explore whether curcumin could …

Iron load toxicity in medicine: from molecular and cellular aspects to clinical implications

GJ Kontoghiorghes - International Journal of Molecular Sciences, 2023 - mdpi.com
Iron is essential for all organisms and cells. Diseases of iron imbalance affect billions of
patients, including those with iron overload and other forms of iron toxicity. Excess iron load …

Assessing the association between important dietary habits and osteoporosis: a genetic correlation and two-sample Mendelian randomization study

J Xu, S Li, Y Zeng, H Si, Y Wu, S Zhang, B Shen - Nutrients, 2022 - mdpi.com
Objective: Osteoporosis (OP) is the most common bone disease. The genetic and metabolic
factors play important roles in OP development. However, the genetic basis of OP is still …

Emerging evidence on the effects of dietary factors on the gut microbiome in colorectal cancer

S Appunni, M Rubens, V Ramamoorthy, R Tonse… - Frontiers in …, 2021 - frontiersin.org
Dietary factors have important role in modulating the gut microbiome, which in-turn regulates
the molecular events in colonic mucosa. The composition and resulting metabolism of the …