Abstract Major Depressive Disorder (MDD) is an affective disorder with sustained negative
affect and difficulties experiencing positive affect as its hallmark features. Previous work also …

Understanding the neural substrates of depression is crucial for diagnosis and treatment.
Here, we review recent studies of functional and effective connectivity in depression, in …

Importance Major depressive disorder is prevalent and impairing. Parsing
neurocomputational substrates of reinforcement learning in individuals with depression may …

Anhedonia is one of the core symptoms of major depressive disorder (MDD), which is often
inadequately treated by traditional antidepressants. The modern framework of anhedonia …

Encountering another's suffering can elicit both empathic distress and empathic care—the
warm desire to affiliate. It remains unclear whether these two feelings can be accurately and …

Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder. An important
diagnostic feature of PTSD is anhedonia, which may result from deficits in reward …

Background The causes of major depressive disorder (MDD), as one of the most common
psychiatric disorders, still remain unclear. Neuroimaging has substantially contributed to …

Despite its high toll on society, there has been little recent improvement in treatment efficacy
for major depressive disorder (MDD). The identification of biological markers of successful …

Most psychiatric disorders do not occur in isolation, and most psychiatric symptom
dimensions are not uniquely expressed within a single diagnostic category. Current …

Background The ability to cognitively control emotions is critical for mental health. Previous
studies have identified the dorsolateral prefrontal cortex (dlPFC) as a core region in …