Senile osteoporosis: the involvement of differentiation and senescence of bone marrow stromal cells

A Qadir, S Liang, Z Wu, Z Chen, L Hu… - International journal of …, 2020 - mdpi.com
Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

Treatment of osteoporotic vertebral fractures

S Prost, S Pesenti, S Fuentes, P Tropiano… - … & Traumatology: Surgery …, 2021 - Elsevier
Osteoporosis is a public health problem that is contributing to an increasing number of
osteoporotic vertebral fractures. The aim of this lecture is to summarize the current state of …

The osteoporosis treatment gap in patients at risk of fracture in European primary care: a multi-country cross-sectional observational study

E McCloskey, J Rathi, S Heijmans, M Blagden… - Osteoporosis …, 2021 - Springer
This study in 8 countries across Europe found that about 75% of elderly women seen in
primary care who were at high risk of osteoporosis-related fractures were not receiving …

Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

[HTML][HTML] Advances in the interaction between endoplasmic reticulum stress and osteoporosis

M Zhong, Z Wu, Z Chen, Q Ren, J Zhou - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The endoplasmic reticulum (ER) is the main site for protein synthesis, folding, and secretion,
and accumulation of the unfolded/misfolded proteins in the ER may induce ER stress. ER …

Global, regional, and national burden of low bone mineral density from 1990 to 2019: results from the global burden of disease study 2019

Y Dong, H Kang, R Peng, K Song, Q Guo… - Frontiers in …, 2022 - frontiersin.org
Objective We aim to explore the global spatial prevalence and temporal trends of the burden
of low bone mineral density (LBMD) worldwide, due to a lack of related studies. Design …

Refracture and mortality following hospitalization for severe osteoporotic fractures: the Fractos Study

C Roux, T Thomas, J Paccou, G Bizouard… - Journal of Bone and …, 2021 - academic.oup.com
Severe osteoporotic fractures (hip, proximal humerus, pelvic, vertebral and multiple rib
fractures) carry an increased risk of mortality. This retrospective cohort study in the French …

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

ZQ Wen, J Lin, WQ Xie, YH Shan, GH Zhen… - Military Medical …, 2023 - Springer
Degenerative musculoskeletal diseases are structural and functional failures of the
musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc …

The Belgian Bone Club 2020 guidelines for the management of osteoporosis in postmenopausal women

D Sanchez-Rodriguez, P Bergmann, JJ Body… - Maturitas, 2020 - Elsevier
Purpose To provide updated evidence-based guidelines for the management of
osteoporosis in postmenopausal women in Belgium. Methods The Belgian Bone Club (BBC) …

M1 macrophage‐derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA‐98/DUSP1/JNK axis

L Yu, M Hu, X Cui, D Bao, Z Luo, D Li, L Li… - Cell Biology …, 2021 - Wiley Online Library
Macrophages (Mφs) are master regulators of the immune response and may serve as
therapeutic targets in aging societies. This study aimed to determine the function of M1Mφ …