The blood-brain barrier (BBB) is a dynamic structure that protects the brain from harmful
blood-borne, endogenous and exogenous substances and maintains the homeostatic …

Vascular dementia (VaD) is the second most common form of dementia after Alzheimer's
disease (AD); where Alzheimer's accounts for 60–70% of cases of dementia and VaD …

Abstract Background Approximately 70% of Alzheimer's disease (AD) patients have co-
morbid vascular contributions to cognitive impairment and dementia (VCID); this highly …

Reduced middle cerebral artery blood velocity (MCAv) and flow pulsatility are contributors to
age-related cerebrovascular disease pathogenesis. It is unknown whether the rate of …

Background: The risk of aneurysmal subarachnoid hemorrhage (aSAH) is increased in
postmenopausal women compared with men of similar age, suggesting a role for sex …

Background Alzheimer's disease (AD) is notably associated with cognitive decline resulting
from impaired function of hippocampal and cortical areas; however, several other domains …

Background Damage to the cerebral vasculature can lead to vascular contributions to
cognitive impairment and dementia (VCID). A reduction in blood flow to the brain leads to …

Food intake and energy expenditure are sensed and processed by multiple brain centres to
uphold energy homeostasis. Evidence from the past decade points to the brain vasculature …

Background We investigated incidence and outcome of spontaneous intracerebral
hemorrhage (ICH) in a population‐based stroke registry and provided data to inform on the …

Background Radiation therapy is the standard of care for central nervous system tumours.
Despite the success of radiation therapy in reducing tumour mass, irradiation (IR)-induced …