Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum
β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to …

Antibiotic resistance has increased markedly in gram-negative bacteria over the last two
decades, and in many cases has been associated with increased mortality and healthcare …

Mobile genetic elements (MGEs) that frequently transfer within and between bacterial
species play a critical role in bacterial evolution, and often carry key accessory genes that …

Antimicrobial resistance is an urgent and growing problem worldwide, both for human and
animal health. In the animal health sector actions have been taken as concerns grow …

The increasing incidence of antimicrobial resistance (AMR) presents a global crisis to
healthcare, with longstanding antimicrobial agents becoming less effective at treating and …

Klebsiella pneumoniae is among the most common causes of hospital-acquired infections
and has emerged as an urgent threat to public health due to carbapenem antimicrobial …

Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health,
leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly …

Multidrug-resistant (MDR) Klebsiella pneumoniae represents an increasing threat to human
health, causing difficult-to-treat infections with a high mortality rate. Since colistin is one of …

Purpose Carbapenems are considered the most efficient antibiotic used in the treatment of
nosocomial infections. Carbapenem-resistant Gram-negative rods are becoming a serious …