Salivary Extracellular Vesicles: Biomarkers and Beyond in Human Diseases

J Wu, G Liu, R Jia, J Guo - International Journal of Molecular Sciences, 2023 - mdpi.com
Extracellular vesicles, as bioactive molecules, have been extensively studied. There are
abundant studies in the literature on their biogenesis, secretion, structure, and content, and …

The post-translational modifications of human salivary peptides and proteins evidenced by top-down platforms

I Messana, B Manconi, T Cabras… - International Journal of …, 2023 - mdpi.com
In this review, we extensively describe the main post-translational modifications that give
rise to the multiple proteoforms characterized to date in the human salivary proteome and …

A Ti/Nb-functionalized COF material based on IMAC strategy for efficient separation of phosphopeptides and phosphorylated exosomes

X Zhang, Q Feng, Z Xie, F Xu, Y Yan, C Ding - Analytical and Bioanalytical …, 2022 - Springer
In this work, on the basis of an immobilized metal ion affinity chromatography enrichment
strategy, a new kind of covalent organic framework (COF) material for enrichment of …

Recent research on material-based methods for isolation of extracellular vesicles

M Chen, J Li, Y Lin, X Li, Y Yu, S Zhou, Q Zhang… - Analytical …, 2024 - pubs.rsc.org
Extracellular vesicles (EVs) are nanoparticles secreted by cells with closed phospholipid
bilayer structure, which can participate in various physiological and pathological processes …

Ti4+ functionalized zirconium metal-organic frameworks with polymer brushes for specific identification of phosphopeptides in human serum and skimmed milk

J Chen, D Wang, B Wang, C Zhou, CF Ding… - Analytical and …, 2024 - Springer
In the present study, click chemistry and Schiff base reactions were simultaneously applied
to prepare polymer brush (PEG)–functionalized MOF materials (UiO-66-NH2) and …

Hidden in plain sight–Extracellular vesicles in saliva and sputum as biomarkers of lung cancer

G Bruin - 2022 - studenttheses.uu.nl
Lung cancer causes the most deaths of any cancer worldwide. An important reason for this
is the fact that the disease is often diagnosed too late. Easier methods for the early detection …