Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome
J Wang, D Wu, H Guo, M Li - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is one of the most common systemic reproductive
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
Resistance to the insulin and elevated level of androgen: A major cause of polycystic ovary syndrome
H Ding, J Zhang, F Zhang, S Zhang, X Chen… - Frontiers in …, 2021 - frontiersin.org
PCOS has a wide range of negative impacts on women's health and is one of the most
frequent reproductive systemic endocrine disorders. PCOS has complex characteristics and …
frequent reproductive systemic endocrine disorders. PCOS has complex characteristics and …
Diagnosis and management of polycystic ovary syndrome in adolescents
Polycystic ovary syndrome (PCOS) is a common female reproductive disorder that often
manifests during adolescence and is associated with disruptions in health-related quality of …
manifests during adolescence and is associated with disruptions in health-related quality of …
Are the antidepressant effects of insulin-sensitizing medications related to improvements in metabolic markers?
T Toba-Oluboka, K Vochosková, T Hajek - Translational Psychiatry, 2022 - nature.com
Insulin-sensitizing medications were originally used in psychiatric practice to treat weight
gain and other metabolic side effects that accompany the use of mood stabilizers …
gain and other metabolic side effects that accompany the use of mood stabilizers …
Metformin improves the depression symptoms of women with polycystic ovary syndrome in a lifestyle modification program
F AlHussain, Y AlRuthia, H Al-Mandeel… - Patient preference …, 2020 - Taylor & Francis
Background Metformin is commonly prescribed to manage polycystic ovary syndrome
(PCOS), which is one of the most common endocrine disorders among women of …
(PCOS), which is one of the most common endocrine disorders among women of …
Metformin: A prospective alternative for the treatment of chronic pain
GDC Baeza-Flores, CG Guzmán-Priego… - Frontiers in …, 2020 - frontiersin.org
Metformin (biguanide) is a drug widely used for the treatment of type 2 diabetes. This drug
has been used for 60 years as a highly effective antihyperglycemic agent. The search for the …
has been used for 60 years as a highly effective antihyperglycemic agent. The search for the …
A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions
Background Activation of brain insulin receptors modulates reward sensitivity, inhibitory
control and memory. Variations in the functioning of this mechanism likely associate with …
control and memory. Variations in the functioning of this mechanism likely associate with …
Metformin: a growing journey from glycemic control to the treatment of Alzheimer's disease and depression
M El Massry, LM Alaeddine, L Ali… - Current Medicinal …, 2021 - ingentaconnect.com
Metabolic stress, transduced as an altered cellular redox and energy status, presents as the
main culprit in many diseases, including diabetes. However, its role in the pathology of …
main culprit in many diseases, including diabetes. However, its role in the pathology of …
Disrupting the mood and obesity cycle: the potential role of metformin
Mounting evidence links obesity, metabolic dysfunction, mood, and cognition. Compromised
metabolic health and psychological functioning worsen clinical outcomes, diminish quality of …
metabolic health and psychological functioning worsen clinical outcomes, diminish quality of …
Association between insulin resistance and abnormal menstrual cycle in Chinese patients with polycystic ovary syndrome
J Niu, M Lu, B Liu - Journal of Ovarian Research, 2023 - Springer
Background Polycystic ovary syndrome (PCOS) is a common reproductive endocrine
disorder, which is characterized by insulin resistance (IR) and menstrual cycle disorders. IR …
disorder, which is characterized by insulin resistance (IR) and menstrual cycle disorders. IR …