The chemistry and biological activities of peptides from amphibian skin secretions
X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …
environmental factors including microorganisms, parasites, predators, and physical factors …
Potential therapeutic applications of multifunctional host-defense peptides from frog skin as anti-cancer, anti-viral, immunomodulatory, and anti-diabetic agents
Frog skin constitutes a rich source of peptides with a wide range of biological properties.
These include host-defense peptides with cytotoxic activities against bacteria, fungi …
These include host-defense peptides with cytotoxic activities against bacteria, fungi …
Neuroprotective and anti‐apoptotic effects of liraglutide on SH‐SY 5Y cells exposed to methylglyoxal stress
MK Sharma, J Jalewa, C Hölscher - Journal of neurochemistry, 2014 - Wiley Online Library
Abstract Glucagon‐like peptide 1 (GLP‐1) is a growth factor that has demonstrated
neuroprotective properties in a range of studies. In an APPswe/PS1ΔE9 mouse model of …
neuroprotective properties in a range of studies. In an APPswe/PS1ΔE9 mouse model of …
Antimicrobial peptides from amphibian innate immune system as potent antidiabetic agents: a literature review and bioinformatics analysis
H Soltaninejad, H Zare-Zardini… - Journal of Diabetes …, 2021 - Wiley Online Library
Antimicrobial peptides, as an important member of the innate immune system, have various
biological activities in addition to antimicrobial activity. There are some AMPs with …
biological activities in addition to antimicrobial activity. There are some AMPs with …
Structure and biological functions of β-hairpin antimicrobial peptides
PV Panteleev, IA Bolosov, SV Balandin… - Acta Naturae …, 2015 - cyberleninka.ru
Antimicrobial peptides (AMPs) are evolutionarily ancient factors of the innate immune
system that serve as a crucial first line of defense for humans, animals, and plants against …
system that serve as a crucial first line of defense for humans, animals, and plants against …
Peptide TK-HR from the Skin of Chinese Folk Medicine Frog Hoplobatrachus Rugulosus Accelerates Wound Healing via the Activation of the Neurokinin-1 Receptor
J Wu, W Xiong, J Li, H Liao, J Chai… - Journal of Medicinal …, 2023 - ACS Publications
Wound healing is a complex process and remains a considerable challenge in clinical trials
due to the lack of ideal therapeutic drugs. Here, a new peptide TK-HR identified from the …
due to the lack of ideal therapeutic drugs. Here, a new peptide TK-HR identified from the …
The first Brevinin-1 antimicrobial peptide with LPS-neutralizing and anti-inflammatory activities in vitro and in vivo
M Tian, K Wang, Y Liang, J Chai, J Wu… - Frontiers in …, 2023 - frontiersin.org
Antimicrobial peptide is one important component of the first protective barrier of organisms.
They not only have potent antimicrobial activity which can protect the body from the invading …
They not only have potent antimicrobial activity which can protect the body from the invading …
Evaluation of the Antidiabetic and Insulin Releasing Effects of A. squamosa, Including Isolation and Characterization of Active Phytochemicals
Annona squamosa is generally referred to as a 'custard apple'. Antidiabetic actions of hot
water extract of Annona squamosa (HWAS) leaves together with isolation of active …
water extract of Annona squamosa (HWAS) leaves together with isolation of active …
Peptides from frog skin with potential for development into agents for Type 2 diabetes therapy
Several frog skin peptides, first identified as result of their antimicrobial or
immunomodulatory activities, have subsequently been shown to stimulate insulin release …
immunomodulatory activities, have subsequently been shown to stimulate insulin release …
Investigational insulin secretagogues for type 2 diabetes
AJ Scheen - Expert opinion on investigational drugs, 2016 - Taylor & Francis
Introduction: Insulin secretory defects are a key feature in the pathophysiology of type 2
diabetes (T2D). Classical insulin-secreting agents such as sulfonlyureas stimulate insulin …
diabetes (T2D). Classical insulin-secreting agents such as sulfonlyureas stimulate insulin …