Metabolomics in cancer research and emerging applications in clinical oncology

DR Schmidt, R Patel, DG Kirsch… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M Wilson, O Andronesi, PB Barker… - Magnetic resonance …, 2019 - Wiley Online Library
Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …

Clinical proton MR spectroscopy in central nervous system disorders

G Öz, JR Alger, PB Barker, R Bartha, A Bizzi, C Boesch… - Radiology, 2014 - pubs.rsna.org
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …

Recent advances in parallel imaging for MRI

J Hamilton, D Franson, N Seiberlich - Progress in nuclear magnetic …, 2017 - Elsevier
Abstract Magnetic Resonance Imaging (MRI) is an essential technology in modern
medicine. However, one of its main drawbacks is the long scan time needed to localize the …

[HTML][HTML] Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression

E Haroon, CC Fleischer, JC Felger, X Chen… - Molecular …, 2016 - nature.com
Inflammation and altered glutamate metabolism are two pathways implicated in the
pathophysiology of depression. Interestingly, these pathways may be linked given that …

Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer

K Sonkar, V Ayyappan, CM Tressler… - NMR in …, 2019 - Wiley Online Library
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: background and experts' consensus recommendations

R Kreis, V Boer, IY Choi, C Cudalbu… - NMR in …, 2021 - Wiley Online Library
With a 40‐year history of use for in vivo studies, the terminology used to describe the
methodology and results of magnetic resonance spectroscopy (MRS) has grown …

[HTML][HTML] Key clinical benefits of neuroimaging at 7 T

S Trattnig, E Springer, W Bogner, G Hangel, B Strasser… - Neuroimage, 2018 - Elsevier
The growing interest in ultra-high field MRI, with more than 35.000 MR examinations already
performed at 7 T, is related to improved clinical results with regard to morphological as well …

A subspace approach to high‐resolution spectroscopic imaging

F Lam, ZP Liang - Magnetic resonance in medicine, 2014 - Wiley Online Library
Purpose To accelerate spectroscopic imaging using sparse sampling of‐space and
subspace (or low‐rank) modeling to enable high‐resolution metabolic imaging with good …