Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Implant fibrosis and the underappreciated role of myofibroblasts in the foreign body reaction

N Noskovicova, B Hinz, P Pakshir - Cells, 2021 - mdpi.com
Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting

K Chen, D Henn, M Januszyk, JA Barrera… - Science Translational …, 2022 - science.org
Burns and other traumatic injuries represent a substantial biomedical burden. The current
standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which …

[HTML][HTML] Nanofabrication through molding

Z Liu, N Liu, J Schroers - Progress in Materials Science, 2022 - Elsevier
Nanomolding usually refers to a top-down fabrication method by which a formable or
moldable material is shaped using a mold of nanoscale dimensions. Nanomolding is the …

Thermoplasticity of metallic glasses: Processing and applications

B Sarac, J Eckert - Progress in materials science, 2022 - Elsevier
Owing to their extremely low shear viscosity and fragility, bulk metallic glasses (BMGs) are
envisioned as new net-shaping material replacing conventionally used crystalline metals for …

Biocompatibility evolves: phenomenology to toxicology to regeneration

L Crawford, M Wyatt, J Bryers… - Advanced healthcare …, 2021 - Wiley Online Library
The word “biocompatibility,” is inconsistent with the observations of healing for so‐called
biocompatible biomaterials. The vast majority of the millions of medical implants in humans …

Re-establishment of macrophage homeostasis by titanium surface modification in type II diabetes promotes osseous healing

RSB Lee, SM Hamlet, HJ Moon, S Ivanovski - Biomaterials, 2021 - Elsevier
Titanium surface mediated immunomodulation may address compromised post-implantation
bone healing in diabetes mellitus. To assess in vitro phenotypic changes, M1 and M2 …

Nanotopographical cues tune the therapeutic potential of extracellular vesicles for the treatment of aged skeletal muscle injuries

K Wang, N Frey, A Garcia, K Man, Y Yang, A Gualerzi… - ACS …, 2023 - ACS Publications
Skeletal muscle regeneration relies on the tightly temporally regulated lineage progression
of muscle stem/progenitor cells (MPCs) from activation to proliferation and, finally …

Hydrophilic titanium surface‐induced macrophage modulation promotes pro‐osteogenic signalling

SM Hamlet, RSB Lee, HJ Moon… - Clinical Oral …, 2019 - Wiley Online Library
Objectives As biomaterial‐induced modulation of mediators of the immune response may be
a potential therapeutic approach to enhance wound healing events, the aim of this study …

Effects of hydroxyapatite surface nano/micro-structure on osteoclast formation and activity

F Chen, M Wang, J Wang, X Chen, X Li… - Journal of Materials …, 2019 - pubs.rsc.org
The surface structure of calcium phosphate (CaP) ceramic plays an important role in its
osteoinductivity; however, little is known about its effects on osteoclastogenesis. In this …