[HTML][HTML] Evaluating cognitive disturbances as treatment target and predictor of antidepressant action in major depressive disorder: a NeuroPharm study

VH Dam, DS Stenbæk, K Köhler-Forsberg, C Ip… - Translational …, 2022 - nature.com
Cognitive disturbances in major depressive disorder (MDD) constitute a critical treatment
target and hold promise as an early predictor of antidepressant treatment response; yet their …

[HTML][HTML] Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression

A Jorgensen, K Köhler-Forsberg, T Henriksen… - Translational …, 2022 - nature.com
Previous studies have indicated that antidepressants that inhibit the serotonin transporter
reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a …

Serotonin 4 receptor brain binding in major depressive disorder and association with memory dysfunction

K Köhler-Forsberg, VH Dam, B Ozenne… - JAMA …, 2023 - jamanetwork.com
Importance The cerebral serotonin 4 (5-HT 4) receptor is a promising novel target for
treatment of major depressive disorder (MDD), and pharmacological stimulation of the 5-HT …

[HTML][HTML] Association between inflammation and cognition: Triangulation of evidence using a population-based cohort and Mendelian randomization analyses

C Slaney, HM Sallis, HJ Jones, C Dardani… - Brain, Behavior, and …, 2023 - Elsevier
Background Inflammation is associated with cognitive functioning and dementia in older
adults, but whether inflammation is related to cognitive functioning in youth and whether …

[HTML][HTML] Harnessing temperament to elucidate the complexities of serotonin function

JW Kanen, TW Robbins, IN Trofimova - Current Opinion in Behavioral …, 2022 - Elsevier
Highlights•Effects of acute tryptophan depletion (ATD) to reduce central 5-HT on emotions
are reviewed.•These jointly depend on both situational context and temperamental trait …

Emotional faces processing in major depressive disorder and prediction of antidepressant treatment response: a NeuroPharm study

PM Fisher, B Ozenne, M Ganz… - Journal of …, 2022 - journals.sagepub.com
Background: Major depressive disorder (MDD) is a prevalent neuropsychiatric illness for
which it is important to resolve underlying brain mechanisms. Current treatments are often …

[HTML][HTML] Stress-Hormone Dynamics and Working Memory in Healthy Women Who Use Oral Contraceptives Versus Non-Users

ES Høgsted, C Borgsted, VH Dam, A Nasser… - Frontiers in …, 2021 - frontiersin.org
Background Women who use oral contraceptives (OCs) may have a higher risk of
developing a depression, which is associated with both vulnerability to stress and cognitive …

[HTML][HTML] Deep phenotyping towards precision psychiatry of first-episode depression—the Brain Drugs-Depression cohort

KHR Jensen, VH Dam, M Ganz, PMD Fisher, CT Ip… - BMC psychiatry, 2023 - Springer
Abstract Background Major Depressive Disorder (MDD) is a heterogenous brain disorder,
with potentially multiple psychosocial and biological disease mechanisms. This is also a …

[HTML][HTML] The pattern glare and visual memory are disrupted in patients with major depressive disorder

M Wang, X Qi, X Yang, H Fan, Y Dou, W Guo, Q Wang… - BMC psychiatry, 2022 - Springer
Background Visual memory impairment is one of the most commonly complained symptoms
in patients with major depressive disorder (MDD). Pattern glare is also a distorted visual …

Cambridge Neuropsychological Test Automated Battery (CANTAB)

C Langley, BJ Sahakian, TW Robbins - The SAGE Handbook of …, 2023 - torrossa.com
The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a computerized
neurocognitive assessment system administered using an adaptive touchscreen. CANTAB …