Neural control of the lower urinary tract: peripheral and spinal mechanisms

L Birder, W De Groat, I Mills, J Morrison… - … : Official Journal of …, 2010 - Wiley Online Library
This review deals with individual components regulating the neural control of the urinary
bladder. This article will focus on factors and processes involved in the two modes of …

Animal models in urological disease and sexual dysfunction

G McMurray, JH Casey… - British journal of …, 2006 - Wiley Online Library
There are several conditions associated with dysfunction of the lower urinary tract or which
result in a reduction in the ability to engage in satisfactory sexual function and result in …

Comparison of levator ani muscle defects and function in women with and without pelvic organ prolapse

JOL DeLancey, DM Morgan, DE Fenner… - Obstetrics & …, 2007 - journals.lww.com
BACKGROUND: To compare levator ani defects and pelvic floor function among women
with prolapse and controls. METHODS: Levator ani structure and function were measured in …

Failure of elastic fiber homeostasis leads to pelvic floor disorders

X Liu, Y Zhao, B Pawlyk, M Damaser, T Li - The American journal of …, 2006 - Elsevier
Pelvic floor disorders, a group of conditions affecting adult women, include pelvic organ
prolapse and urinary incontinence. Vaginal childbirth and aging are risk factors, and …

Pudendal nerve stretch during vaginal birth: a 3D computer simulation

KC Lien, DM Morgan, JOL Delancey… - American journal of …, 2005 - Elsevier
OBJECTIVE: The purpose of this study was to determine the increase in pudendal nerve
branch lengths using a 3D computer model of vaginal delivery. STUDY DESIGN: The main …

Mesenchymal stem cell seeded knitted silk sling for the treatment of stress urinary incontinence

XH Zou, YL Zhi, X Chen, HM Jin, LL Wang, YZ Jiang… - Biomaterials, 2010 - Elsevier
Stress urinary incontinence remains a worldwide problem affecting patients of all ages.
Implantation of suburethral sling is the cornerstone treatment. Current slings have inherent …

Effects of vaginal distension on urethral anatomy and function

TW Cannon, EM Wojcik, CL Ferguson… - BJU …, 2002 - Wiley Online Library
Objective To determine the effect of repeated and prolonged vaginal distension on the leak‐
point pressure (LPP) and urethral anatomy in the female rat, as prolonged vaginal …

External urethral sphincter activity in a rat model of pudendal nerve injury

CW Peng, JJJ Chen, HY Chang… - … : Official Journal of …, 2006 - Wiley Online Library
Aims Pudendal nerve injury in the rat has been a useful animal model for studying stress
urinary incontinence (SUI). However, the effect of pudendal nerve injury on activity of the …

Bone marrow mesenchymal stromal cell therapy for external urethral sphincter restoration in a rat model of stress urinary incontinence

J Corcos, O Loutochin, L Campeau… - Neurourology and …, 2011 - Wiley Online Library
Objective To assess the effect of intra‐sphincteric injections of bone marrow mesenchymal
stromal cells (MSCs) on Valsalva leak point pressure (VLPP) changes in an animal model of …

Tissue engineered bulking agent with adipose-derived stem cells and silk fibroin microspheres for the treatment of intrinsic urethral sphincter deficiency

LB Shi, HX Cai, LK Chen, Y Wu, SA Zhu, XN Gong… - Biomaterials, 2014 - Elsevier
In this study we developed a tissue engineered bulking agent that consisted of adipose-
derived stem cells (ADSCs) and silk fibroin microspheres to treat stress urinary incontinence …