ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

The contribution of the exposome to the burden of cardiovascular disease

T Münzel, M Sørensen, O Hahad… - Nature Reviews …, 2023 - nature.com
Large epidemiological and health impact assessment studies at the global scale, such as
the Global Burden of Disease project, indicate that chronic non-communicable diseases …

[HTML][HTML] Health position paper and redox perspectives-Disease burden by transportation noise

M Sørensen, G Pershagen, JD Thacher, T Lanki… - Redox Biology, 2023 - Elsevier
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …

The crosstalk between Nrf2 and NF-κB pathways in coronary artery disease: Can it be regulated by SIRT6?

E Casper - Life sciences, 2023 - Elsevier
Coronary artery disease (CAD) is the leading cause of death worldwide. Oxidative stress
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …

Pollution and endometriosis: a deep dive into the environmental impacts on women's health

A Vallée, PF Ceccaldi, M Carbonnel… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Background The interaction between pollution and endometriosis is a pressing issue that
demands immediate attention. The impact of pollution, particularly air and water pollution, or …

First evidence of dermo-protective activity of marine sulfur-containing histidine compounds

M Brancaccio, A Milito, CA Viegas, A Palumbo… - Free Radical Biology …, 2022 - Elsevier
Among natural products, ovothiol (ovo), produced by marine invertebrates, bacteria, and
microalgae, is receiving increasing interest for its unique antioxidant properties. Recently …

Pesticides as a risk factor for cognitive impairment: Natural substances are expected to become alternative measures to prevent and improve cognitive impairment

L Wen, X Miao, J Ding, X Tong, Y Wu, Y He… - Frontiers in …, 2023 - frontiersin.org
Pesticides are the most effective way to control diseases, insects, weeds, and fungi. The
central nervous system (CNS) is damaged by pesticide residues in various ways. By …

Anti-Wrinkling Effect of 3,4,5-tri-O-caffeoylquinic Acid from the Roots of Nymphoides peltata through MAPK/AP-1, NF-κB, and Nrf2 Signaling in UVB-Irradiated HaCaT …

TY Kim, NJ Park, BG Jo, BS Lee, MJ Keem, TH Kwon… - Antioxidants, 2023 - mdpi.com
Nymphoides peltata has been widely used pharmacologically in traditional Chinese
medicine to treat heat strangury and polyuria. The aim of this study was to isolate the …

Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

M Lu, J Ji, Y Lv, J Zhao, Y Liu, Q Jiao, T Liu, Y Mou… - Cell Chemical …, 2024 - cell.com
Most BTB-containing E3 ligases homodimerize to recognize a single substrate by engaging
multiple degrons, represented by E3 ligase KEAP1 dimer and its substrate NRF2 …

Vascular redox signaling, endothelial nitric oxide synthase uncoupling, and endothelial dysfunction in the setting of transportation noise exposure or chronic treatment …

T Münzel, A Daiber - Antioxidants & Redox Signaling, 2023 - liebertpub.com
Significance: Cardiovascular disease and drug-induced health side effects are frequently
associated with—or even caused by—an imbalance between the concentrations of reactive …