Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
Oxidative stress response and Nrf2 signaling in aging
H Zhang, KJA Davies, HJ Forman - Free Radical Biology and Medicine, 2015 - Elsevier
Increasing oxidative stress, a major characteristic of aging, has been implicated in a variety
of age-related pathologies. In aging, oxidant production from several sources is increased …
of age-related pathologies. In aging, oxidant production from several sources is increased …
Redox signaling by reactive electrophiles and oxidants
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …
[HTML][HTML] Anti-oxidant and anti-inflammatory activity of ketogenic diet: new perspectives for neuroprotection in Alzheimer's disease
A Pinto, A Bonucci, E Maggi, M Corsi, R Businaro - Antioxidants, 2018 - mdpi.com
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …
Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases
Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in
phospholipids in the brain and retina, is known to play multi-functional roles in brain health …
phospholipids in the brain and retina, is known to play multi-functional roles in brain health …
[HTML][HTML] The cysteine proteome
The cysteine (Cys) proteome is a major component of the adaptive interface between the
genome and the exposome. The thiol moiety of Cys undergoes a range of biologic …
genome and the exposome. The thiol moiety of Cys undergoes a range of biologic …
Lipid peroxidation: physiological levels and dual biological effects
E Niki - Free Radical Biology and Medicine, 2009 - Elsevier
Lipid peroxidation (LPO) has been shown to induce disturbance of membrane organization
and functional loss and modification of proteins and DNA bases, and it has been implicated …
and functional loss and modification of proteins and DNA bases, and it has been implicated …
The 4-hydroxynonenal–protein adducts and their biological relevance: are some proteins preferred targets?
It is well known that oxidative stress and lipid peroxidation (LPO) play a role in physiology
and pathology. The most studied LPO product with pleiotropic capabilities is 4 …
and pathology. The most studied LPO product with pleiotropic capabilities is 4 …
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
A Negre‐Salvayre, C Coatrieux… - British journal of …, 2008 - Wiley Online Library
Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar
glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and Advanced …
glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and Advanced …
Focus on mammalian thioredoxin reductases—important selenoproteins with versatile functions
ESJ Arnér - Biochimica et Biophysica Acta (BBA)-General Subjects, 2009 - Elsevier
BACKGROUND: Thioredoxin systems, involving redox active thioredoxins and thioredoxin
reductases, sustain a number of important thioredoxin-dependent pathways. These systems …
reductases, sustain a number of important thioredoxin-dependent pathways. These systems …