[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Complexation-induced resolution enhancement of 3D-printed hydrogel constructs

J Gong, CCL Schuurmans, AM Genderen… - Nature …, 2020 - nature.com
Abstract Three-dimensional (3D) hydrogel printing enables production of volumetric
architectures containing desired structures using programmed automation processes. Our …

[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Coacervates: Recent developments as nanostructure delivery platforms for therapeutic biomolecules

E Ban, A Kim - International Journal of Pharmaceutics, 2022 - Elsevier
Coacervation is a liquid–liquid phase separation that can occur in solutions of
macromolecules through self-assembly or electrostatic interactions. Recently, coacervates …

[HTML][HTML] Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2+ breast cancer after breast-conserving …

X Chen, M Wang, X Yang, Y Wang, L Yu, J Sun… - Theranostics, 2019 - ncbi.nlm.nih.gov
A high risk of local relapse is the main challenge of HER2+ breast cancer after breast-
conserving surgery. We aimed to develop a long-acting delivery system for Herceptin, a …

Recent advances in microgels: from biomolecules to functionality

Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi… - Small, 2022 - Wiley Online Library
The emerging applications of hydrogel materials at different length scales, in areas ranging
from sustainability to health, have driven the progress in the design and manufacturing of …

Macro-and microphase separated protein-polyelectrolyte complexes: Design parameters and current progress

JM Horn, RA Kapelner, AC Obermeyer - Polymers, 2019 - mdpi.com
Protein-containing polyelectrolyte complexes (PECs) are a diverse class of materials,
composed of two or more oppositely charged polyelectrolytes that condense and phase …

Novel strategies for the treatment of osteoarthritis based on biomaterials and critical molecular signaling

X Huang, Z Wang, H Wang, D Chen, L Tong - Journal of Materials Science …, 2023 - Elsevier
Osteoarthritis (OA) is a degenerative disease involving entire joint. It is often initiated from
the low-grade inflammation in synovial tissue and then affects articular cartilage and …

Aggressive strategies for regenerating intervertebral discs: stimulus-responsive composite hydrogels from single to multiscale delivery systems

X Gao, X Zhang, R Zhang, D Yu, X Chen… - Journal of Materials …, 2022 - pubs.rsc.org
As our research on the physiopathology of intervertebral disc degeneration (IVD
degeneration, IVDD) has advanced and tissue engineering has rapidly evolved, cell …