Once and only once: mechanisms of centriole duplication and their deregulation in disease
EA Nigg, AJ Holland - Nature reviews Molecular cell biology, 2018 - nature.com
Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …
The centrosome and its duplication cycle
The centrosome was discovered in the late 19th century when mitosis was first described.
Long recognized as a key organelle of the spindle pole, its core component, the centriole …
Long recognized as a key organelle of the spindle pole, its core component, the centriole …
Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization
V Mennella, B Keszthelyi, KL McDonald, B Chhun… - Nature cell …, 2012 - nature.com
As the main microtubule-organizing centre in animal cells, the centrosome has a
fundamental role in cell function. Surrounding the centrioles, the pericentriolar material …
fundamental role in cell function. Surrounding the centrioles, the pericentriolar material …
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes
Centrioles are essential for the formation of cilia and flagella. They also form the core of the
centrosome, which organizes microtubule arrays important for cell shape, polarity, motility …
centrosome, which organizes microtubule arrays important for cell shape, polarity, motility …
[HTML][HTML] Structural basis of the 9-fold symmetry of centrioles
The centriole, and the related basal body, is an ancient organelle characterized by a
universal 9-fold radial symmetry and is critical for generating cilia, flagella, and centrosomes …
universal 9-fold radial symmetry and is critical for generating cilia, flagella, and centrosomes …
A helical inner scaffold provides a structural basis for centriole cohesion
The ninefold radial arrangement of microtubule triplets (MTTs) is the hallmark of the
centriole, a conserved organelle crucial for the formation of centrosomes and cilia. Although …
centriole, a conserved organelle crucial for the formation of centrosomes and cilia. Although …
Towards a molecular architecture of centriole assembly
P Gönczy - Nature reviews Molecular cell biology, 2012 - nature.com
The centriole is an evolutionarily conserved macromolecular structure that is crucial for the
formation of flagella, cilia and centrosomes. The ultrastructure of the centriole was first …
formation of flagella, cilia and centrosomes. The ultrastructure of the centriole was first …
Structures of SAS-6 suggest its organization in centrioles
M van Breugel, M Hirono, A Andreeva, H Yanagisawa… - Science, 2011 - science.org
Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules
strictly required to template cilia and flagella. The highly conserved protein SAS-6 …
strictly required to template cilia and flagella. The highly conserved protein SAS-6 …
The centriole duplication cycle
EN Fırat-Karalar, T Stearns - … Transactions of the Royal …, 2014 - royalsocietypublishing.org
Centrosomes are the main microtubule-organizing centre of animal cells and are important
for many critical cellular and developmental processes from cell polarization to cell division …
for many critical cellular and developmental processes from cell polarization to cell division …
[HTML][HTML] Building the centriole
J Azimzadeh, WF Marshall - Current Biology, 2010 - cell.com
Centrioles are conserved microtubule-based organelles that lie at the core of the animal
centrosome and play a crucial role in nucleating the formation of cilia and flagella in most …
centrosome and play a crucial role in nucleating the formation of cilia and flagella in most …