Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …

Biophysical (mechanical and electrical) properties of living cells have been proven to play
important roles in the regulation of various biological activities at the molecular and cellular …

Many transfection techniques can deliver biomolecules into cells, but the dose cannot be
controlled precisely. Delivering well-defined amounts of materials into cells is important for …

Background Nanoinjection—the process of intracellular delivery using vertically configured
nanostructures—is a physical route that efficiently negotiates the plasma membrane, with …

Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

Effective intracellular delivery is a significant impediment to research and therapeutic
applications at all processing scales. Physical delivery methods have long demonstrated the …

In this Tutorial, we provide a discussion of “What are cell membrane resistance (MR) and
capacitance (MC)?” and then give a number of examples to illustrate how cell membranes …

Pulse electric field‐based (PEF) ablation is a technique whereby short high‐intensity electric
fields inducing irreversible electroporation (IRE) are applied to various tissues. Here, we …

Electroporation is a biophysical phenomenon involving an increase in cell membrane
permeability to molecules after a high-pulsed electric field is applied to the tissue. Currently …

While electroporation has been widely used as a physical method for gene transfection in
vitro and in vivo, its application in gene therapy of cardiovascular cells remains challenging …