MicroRNAs in B-cell lymphomas: how a complex biology gets more complex

K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …

Clinical outcome prediction by microRNAs in human cancer: a systematic review

VS Nair, LS Maeda, JPA Ioannidis - Journal of the National …, 2012 - academic.oup.com
Background MicroRNA (miR) expression may have prognostic value for many types of
cancers. However, the miR literature comprises many small studies. We systematically …

miRGate: a curated database of human, mouse and rat miRNA–mRNA targets

E Andres-Leon, D González Peña, G Gomez-Lopez… - Database, 2015 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding elements involved in the post-transcriptional
down-regulation of gene expression through base pairing with messenger RNAs (mRNAs) …

Potentially prognostic miRNAs in HPV-associated oropharyngeal carcinoma

ABY Hui, A Lin, W Xu, L Waldron, B Perez-Ordonez… - Clinical cancer …, 2013 - AACR
Purpose: Deregulation of miRNAs is associated with almost all human malignancies.
Human papillomavirus (HPV)-associated oropharyngeal carcinoma (OPC) has a …

miRNA-based therapies in B cell non-Hodgkin lymphoma

T Fuertes, AR Ramiro, VG de Yebenes - Trends in Immunology, 2020 - cell.com
Non-Hodgkin lymphoma (NHL) is a diverse class of hematological cancers, many of which
arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity …

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma

SB Ng, J Yan, G Huang, V Selvarajan… - Blood, The Journal …, 2011 - ashpublications.org
We performed a comprehensive genome-wide miRNA expression profiling of extranodal
nasal-type natural killer/T-cell lymphoma (NKTL) using formalin-fixed paraffin-embedded …

MicroRNA signatures in B-cell lymphomas

L Di Lisio, M Sánchez-Beato, G Gómez-López… - Blood cancer …, 2012 - nature.com
Accurate lymphoma diagnosis, prognosis and therapy still require additional markers. We
explore the potential relevance of microRNA (miRNA) expression in a large series that …

Role of micro RNA in the pathogenesis of malignant lymphoma

H Tagawa, S Ikeda, K Sawada - Cancer science, 2013 - Wiley Online Library
Micro RNA (mi RNA) are non‐coding regulatory RNA usually consisting of 20− 24
nucleotides. Over the past decade, increases and decreases in mi RNA expression have …

Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis

J Iqbal, Y Shen, Y Liu, K Fu, ES Jaffe… - Blood, The Journal …, 2012 - ashpublications.org
Abstract miRNA deregulation has been implicated in the pathogenesis of mantle cell
lymphoma (MCL). Using a high-throughput quantitative real-time PCR platform, we …

Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity

X Zhao, T Lwin, X Zhang, A Huang, J Wang… - Leukemia, 2013 - nature.com
Abstract c-MYC (hereafter MYC) overexpression has been recognized in aggressive B-cell
lymphomas and linked to adverse prognosis. MYC activation results in widespread …