Proteases are involved in a broad range of physiological processes, including host invasion
by fungal pathogens, and enzymatic inhibition is a key molecular mechanism controlling …

Fungal infections represent a worldwide concern for public health, due to their prevalence
and significant increase in cases each year. Among the most frequent mycoses are those …

Lopinavir is an antiretroviral, antiparasitic agent and recently utilized in treatment of COVID-
19. Unfortunately, lopinavir exhibited poor oral bioavailability due to poor dissolution …

Secreted aspartyl proteases (SAPs) are important enzymes for fungal pathogenicity, playing
a significant role in infection and survival. This article provides insight into how SAPs …

Candida albicans (C. albicans) is a commensal microbiota that resides in humans. However,
in certain cases, C. albicans can infect and cause several diseases to humans. This study …

The genus Fonsecaea is one of the etiological agents of chromoblastomycosis (CBM), a
chronic subcutaneous disease that is difficult to treat. This work aimed to evaluate the effects …

Candida albicans (C. albicans) have long been attributed to various diseases like
candidiasis and systemic diseases and exacerbate the symptoms of immunocompromised …

Candida albicans is the chief etiological agent of candidiasis, a mycosis prevalent in
individuals with acquired immunodeficiency syndrome (AIDS). In recent years, the …

Fungal infections account for more than 140 million cases of severe and life-threatening
conditions each year, causing approximately 1.7 million deaths annually. Candida albicans …

Extracellular proteases are key factors contributing to the virulence of pathogenic fungi from
the genus Candida. Their proteolytic activities are crucial for extracting nutrients from the …