An emphasis on the interaction of signaling pathways highlights the role of miRNAs in the etiology and treatment resistance of gastric cancer

D Fathi, MS Elballal, AE Elesawy, AI Abulsoud… - Life Sciences, 2023 - Elsevier
Gastric cancer (GC) is 4th in incidence and mortality rates globally. Several genetic and
epigenetic factors, including microRNAs (miRNAs), affect its initiation and progression …

Gastric adenocarcinoma

JA Ajani, J Lee, T Sano, YY Janjigian, D Fan… - Nature reviews Disease …, 2017 - nature.com
Gastric cancers, with gastric adenocarcinoma (GAC) as the most common histological type,
impose a considerable global health burden. Although the screening strategies for early …

miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review

HA El-Mahdy, EGE Elsakka, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

Are mast cells MASTers in cancer?

G Varricchi, MR Galdiero, S Loffredo… - Frontiers in …, 2017 - frontiersin.org
Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Eosinophils: The unsung heroes in cancer?

G Varricchi, MR Galdiero, S Loffredo, V Lucarini… - …, 2018 - Taylor & Francis
Prolonged low-grade inflammation or smoldering inflammation is a hallmark of a cancer.
Eosinophils are components of the immune microenvironment that modulates tumor …

Diagnostic, predictive, prognostic, and therapeutic molecular biomarkers in third millennium: a breakthrough in gastric cancer

N Carlomagno, P Incollingo, V Tammaro… - BioMed research …, 2017 - Wiley Online Library
Introduction. Gastric cancer is the fifth most common cancer and the third cause of cancer
death. The clinical outcomes of the patients are still not encouraging with a low rate of 5 …

Gastric biomarkers: a global review

N Baniak, JL Senger, S Ahmed, SC Kanthan… - World journal of surgical …, 2016 - Springer
Background Gastric cancer is an aggressive disease with a poor 5-year survival and large
global burden of disease. The disease is biologically and genetically heterogeneous with a …

Long non-coding RNAs (lncRNAs) as regulators of the PI3K/AKT/mTOR pathway in gastric carcinoma

I Riquelme, P Pérez-Moreno, B Mora-Lagos… - International journal of …, 2023 - mdpi.com
Gastric cancer (GC) represents~ 10% of the global cancer-related deaths, increasingly
affecting the younger population in active stages of life. The high mortality of GC is due to …

COL12A1, a novel potential prognostic factor and therapeutic target in gastric cancer

X Jiang, M Wu, X Xu, L Zhang… - Molecular …, 2019 - spandidos-publications.com
Dysregulation of collagen type XII α1 chain (COL12A1) has been found in several cancer
types and could be involved in tumor progression. However, its clinical significance in …

[HTML][HTML] Implementing liquid biopsies into clinical decision making for cancer immunotherapy

D Quandt, HD Zucht, A Amann, A Wulf-Goldenberg… - Oncotarget, 2017 - ncbi.nlm.nih.gov
During the last decade, novel immunotherapeutic strategies, in particular antibodies directed
against immune checkpoint inhibitors, have revolutionized the treatment of different …