A functional perspective on phenotypic heterogeneity in microorganisms

M Ackermann - Nature Reviews Microbiology, 2015 - nature.com
Most microbial communities consist of a genetically diverse assembly of different organisms,
and the level of genetic diversity plays an important part in community properties and …

Shiga toxin-associated hemolytic uremic syndrome: A narrative review

A Joseph, A Cointe, P Mariani Kurkdjian, C Rafat… - Toxins, 2020 - mdpi.com
The severity of human infection by one of the many Shiga toxin-producing Escherichia coli
(STEC) is determined by a number of factors: the bacterial genome, the capacity of human …

Importance of prophages to evolution and virulence of bacterial pathogens

LC Fortier, O Sekulovic - Virulence, 2013 - Taylor & Francis
Bacteriophages, or simply phages, are viruses infecting bacteria. With an estimated 1031
particles in the biosphere, phages outnumber bacteria by a factor of at least 10 and not …

Pathogenic Escherichia coli

JB Kaper, JP Nataro, HLT Mobley - Nature reviews microbiology, 2004 - nature.com
Few microorganisms are as versatile as Escherichia coli. An important member of the
normal intestinal microflora of humans and other mammals, E. coli has also been widely …

[HTML][HTML] Bacteriophage lambda: Early pioneer and still relevant

SR Casjens, RW Hendrix - Virology, 2015 - Elsevier
Molecular genetic research on bacteriophage lambda carried out during its golden age from
the mid-1950s to mid-1980s was critically important in the attainment of our current …

Virulence and immunomodulatory roles of bacterial outer membrane vesicles

TN Ellis, MJ Kuehn - Microbiology and molecular biology reviews, 2010 - Am Soc Microbiol
Outer membrane (OM) vesicles are ubiquitously produced by Gram-negative bacteria during
all stages of bacterial growth. OM vesicles are naturally secreted by both pathogenic and …

Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion

H Brüssow, C Canchaya… - … and molecular biology …, 2004 - Am Soc Microbiol
Comparative genomics demonstrated that the chromosomes from bacteria and their viruses
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …

Enterohemorrhagic E. coli (EHEC) pathogenesis

Y Nguyen, V Sperandio - Frontiers in cellular and infection …, 2012 - frontiersin.org
Enterohemorrhagic Escherichia coli (EHEC) serotype O157: H7 is a human pathogen
responsible for outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) …

Pathogenicity assessment of Shiga toxin‐producing Escherichia coli (STEC) and the public health risk posed by contamination of food with STEC

EFSA Biohaz Panel, K Koutsoumanis, A Allende… - Efsa …, 2020 - Wiley Online Library
The provisional molecular approach, proposed by EFSA in 2013, for the pathogenicity
assessment of Shiga toxin‐producing Escherichia coli (STEC) has been reviewed. Analysis …

Shiga toxin-producing Escherichia coli: An overview

CL Gyles - Journal of animal science, 2007 - academic.oup.com
The objective of this review is to highlight the importance of cattle in human disease due to
Shiga toxin-producing Escherichia coli (STEC) and to discuss features of STEC that are …