The optimal performance of the cardiovascular system, as well as the break-down of this
performance with disease, both involve complex biomechanical interactions between the …

Due to the cyclic function of the human heart, pressure and flow in the circulation are
pulsatile rather than continuous. Addressing pulsatile haemodynamics starts with the most …

Evidence exists that heart failure (HF) has an overall impact of 1-2% in the global population
being often associated with comorbidities that contribute to increased disease prevalence …

Objectives Inorganic nitrate is one of the most effective compounds in beetroot for improving
cardiovascular function due to its conversion to nitric oxide in the body. This review and …

Excessive pressure and flow pulsatility in first-generation branch arteries are associated with
microvascular damage in high-flow organs like brain and kidneys. However, the contribution …

Whereas traditional understanding of left ventricular afterload was focused on a steady-state
circulation model with continuous pressures and flow, a more realistic concept is emerging …

Aims: To systematically evaluate the efficacy and safety of the Guanxinshutong capsule
(GXST) combined with Western medicine (WM) in treating stable angina pectoris (SAP) …

Cardiovascular diseases (CVDs) are often associated with impaired nitric oxide (NO)
bioavailability, a critical pathophysiological alteration in CVDs and an important target for …

Background Approximately half of patients with heart failure have a preserved ejection
fraction (HFpEF). To date, only SGLT-2i, ARNi, and MRAs treatments have been shown to …

At any given location along the arterial tree, blood pressure and flow (or flow velocity) are
intricately linked and mutually dependent. Factors governing this relationship depend on …