Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited
cardiomyopathy that can lead to sudden cardiac death and heart failure. Our understanding …

Given the global burden of heart failure, strategies to understand the underlying cause or to
provide prognostic information are critical to reducing the morbidity and mortality associated …

Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …

Background: Peripartum cardiomyopathy (PPCM) occurs in≈ 1: 2000 deliveries in the
United States and worldwide. The genetic underpinnings of PPCM remain poorly defined …

Hypertrophic cardiomyopathy (HCM) was traditionally described as an autosomal dominant
Mendelian disease but is now increasingly recognized as having a complex genetic …

Dilated cardiomyopathy (DCM) is characterized by left ventricular dilatation and,
consecutively, contractile dysfunction. The causes of DCM are heterogeneous. DCM often …

Dilated cardiomyopathy is conventionally defined as the presence of left ventricular or
biventricular dilatation or systolic dysfunction in the absence of abnormal loading conditions …

Background: Filamin C truncating variants (FLNCtv) cause a form of arrhythmogenic
cardiomyopathy: the mode of presentation, natural history, and risk stratification of FLNCtv …

Filamin C (FLNC) variants are associated with cardiac and muscular phenotypes. Originally,
FLNC variants were described in myofibrillar myopathy (MFM) patients. Later, high …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …