Molecular mechanisms in clear cell renal cell carcinoma: role of miRNAs and hypermethylated miRNA genes in crucial oncogenic pathways and processes

EA Braga, MV Fridman, VI Loginov, AA Dmitriev… - Frontiers in …, 2019 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it
has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has …

Overview of host miRNA properties and their association with epigenetics, long non-coding RNAs, and Xeno-infectious factors

S Heydarzadeh, M Ranjbar, F Karimi, F Seif… - Cell & Bioscience, 2021 - Springer
MicroRNA-derived structures play impressive roles in various biological processes. So
dysregulation of miRNAs can lead to different human diseases. Recent studies have …

MicroRNA signature in renal cell carcinoma

S Ghafouri-Fard, Z Shirvani-Farsani, W Branicki… - Frontiers in …, 2020 - frontiersin.org
Renal cell carcinoma (RCC) includes 2.2% of all diagnosed cancers and 1.8% of cancer-
related mortalities. The available biomarkers or screening methods for RCC suffer from lack …

The biological roles and clinical implications of microRNAs in clear cell renal cell carcinoma

Y He, C Chen, Z Shi - Journal of cellular physiology, 2018 - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) accounts for about 3% of tumors in adults as well as
85% of all primary renal carcinoma. And it is the third most predominant urological …

NDUFA4L2 is associated with clear cell renal cell carcinoma malignancy and is regulated by ELK1

L Wang, Z Peng, K Wang, Y Qi, Y Yang, Y Zhang, X An… - PeerJ, 2017 - peerj.com
Background Clear cell renal cell carcinoma (ccRCC) is the most common and lethal cancer
of the adult kidney. However, its pathogenesis has not been fully understood till now, which …

MicroRNAs implications in the onset, diagnosis, and prognosis of osteosarcoma

N Ebrahimi, S Aslani, F Babaie… - Current Molecular …, 2021 - ingentaconnect.com
Osteosarcoma (OS) is a primary bone malignancy, which has a high incidence in children
and adolescents. The affected cells and tissues show the properties of drug-resistance and …

[HTML][HTML] Construction and validation of a novel ten miRNA-pair based signature for the prognosis of clear cell renal cell carcinoma

Y Wang, Z Shen, S Mo, L Dai, B Song, W Gu… - Translational …, 2022 - Elsevier
Background Clear cell renal cell carcinoma (ccRCC) is the most predominate pathological
subtype of renal cell carcinoma, causing a recurrence or metastasis rate as high as 20% to …

[HTML][HTML] CHL1 gene polymorphisms increase lung cancer susceptibility

W Tian, X Li, Y Ren, Z Yin, X Quan, C Zheng, B Zhou - Oncotarget, 2018 - ncbi.nlm.nih.gov
Lung cancer represents a complex and malignant cancer. Close Homologue of L1 (CHL1)
gene plays a crucial role in the progress of cancer. The aim of this study is to explore the …

[HTML][HTML] Аберрантная экспрессия и метилирование генов отдельных микроРНК при лимфопролиферативных заболеваниях: обзор литературы

ЕН Воропаева, ОВ Березина… - Journal of Siberian …, 2021 - cyberleninka.ru
В последние десятилетия обнаружено, что микроРНК участвуют практически во всех
клеточных процессах, в том числе в развитии опухолей. В представленном обзоре …

[PDF][PDF] Ανοσοϊστοχημική μελέτη έκφρασης των υπεροξειδασών γλουταθειόνης 1 & 3 (GPX1 και GPX3) στο διαυγοκυτταρικό καρκίνωμα του νεφρού

ΧΑ Μάρκου - 2021 - ir.lib.uth.gr
Renal cell carcinoma is the most common renal cancer form. It affects men 1, 5 to 2 times
more frequently to women and with a mean age of diagnosis 64 years for sporadic and …