Kidney transplantation is the current treatment of choice for patients with end-stage renal
disease. Innovations in transplantation and immunosuppression regimens have greatly …

Falling outside of Lipinski's rule of five, macrocyclic drugs have accessed unique binding
sites of their target receptors unreachable by traditional small molecules. Cyclosporin (e) A …

Objectives: Water and electrolytes disturbances often occur in renal transplant recipients.
The objective is to describe the pathophysiology and the treatment of the most prevalent …

Kidney transplant patients (KTPs), and particularly those with advanced chronic kidney
rejection, may be affected by opportunistic infections, metabolic alterations and vascular and …

TORREGROSA, José V. et al. Tratamiento eficaz de la arteriolopatía urémica calcificante
con bifosfonatos. Nefrología (Madr.)[online]. 2012, vol. 32, n. 3, pp. 329-334. ISSN 0211 …

Cyclosporine is a potent immunosuppressive drug. It has a narrow therapeutic index, and
therefore the measurement of cyclosporine's blood concentration is essential to obtain …

Introduction: Percutaneous renal biopsy remains critical for the workup of renal allograft
dysfunction but is associated with the risk of bleeding. Prophylactic intravenous …

Background: Hyponatremia is one of the most common electrolyte disorders observed in
hospitalized and ambulatory patients. Hyponatremia is associated with increased falls …

La hiperpotasemia es uno de los trastornos hidroelectrolíticos más frecuentes. Puede
representar un problema grave de salud tanto a corto como a largo plazo. Cifras muy …

Although hyperkalemia (HK) is often associated with adverse clinical outcomes in renal
patients, few studies are available in the setting of kidney transplantation. Therefore, we …