Parkinson's disease (PD) is known as a mitochondrial disease. Some even regarded it
specifically as a disorder of the complex I of the electron transport chain (ETC). The ETC is …

The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …

Background Mitochondrial disorders are clinically complex and have highly variable
phenotypes among all inherited disorders. Mutations in mitochon drial DNA (mtDNA) and …

Selective neuronal vulnerability (SNV) of specific neuroanatomical regions such as frontal
cortex (FC) and hippocampus (HC) is characteristic of age-associated neurodegenerative …

Idiopathic inflammatory myopathies (IIM) are a group of rare and heterogeneous
autoimmune diseases, and the most common subtypes are dermatomyositis (DM) and …

Sporadic inclusion body myositis (sIBM) is one of the most common myopathies in elderly
people. Mitochondrial abnormalities at the histological level are present in these patients …

Traumatic brain injury (TBI) causes significant neurological deficits and long‐term
degenerative changes. Primary injury in TBI entails distinct neuroanatomical zones, ie …

Mitochondrial dysfunction and oxidative stress are critical to neurodegeneration in
Parkinson's disease (PD). Mitochondrial dysfunction in PD entails inhibition of the …

Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause
incorrect communication between the nerves and muscles. The specific causes of NMDs are …

Introduction: Human skeletal muscle represents 40% of our body mass and deciphering its
proteome composition to further understand mechanisms regulating muscle function under …