Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Biological systems display a rich phenomenology of states that resemble the physical states
of matter-solid, liquid and gas. These phases result from the interactions between the …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

The formation and recovery of gaps in the vascular endothelium governs a wide range of
physiological and pathological phenomena, from angiogenesis to tumor cell extravasation …

Embryo morphogenesis is impacted by dynamic changes in tissue material properties,
which have been proposed to occur via processes akin to phase transitions (PTs). Here, we …

From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …

Cell-cell adhesion by adherens junctions controls proliferation and cell polarization and is
crucial to maintain epithelial architecture and homeostasis. Downregulation of two of the …

Tissue morphogenesis in multicellular organisms is brought about by spatiotemporal
coordination of mechanical and chemical signals. Extensive work on how mechanical forces …

Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …